专利检索 ap:("Array BioPharma Inc." OR "Loxo Oncology, Inc.") AND inv:"WELCH, Mike" 第 1 页

1.

发明公开
PROCESS FOR THE PREPARATION OF 6-(2-HYDROXY-2-METHYLPROPOXY)-4-(6-(6-((6-METHOXYPYRIDIN-3-YL)METHYL)-3,6-DIAZABICYCLO[3.1.1]HEPTAN-3-YL)PYRIDIN-3-YL)PYRAZOLO[1,5-A]PYRIDINE-3-CARBONITRILE 审中-公开

公开(公告)号：EP3694853A1

公开(公告)日：2020-08-19

申请号：EP18796238.6

申请日：2018-10-10

申请人： Array BioPharma Inc. , Loxo Oncology, Inc.

发明人： EARY, Charles Todd , SPENCER, Stacey , CRANE, Zack , CHANDO, Katelyn , ASSELIN, Sylvie , LIU, Weidong , WELCH, Mike , COOK, Adam , KOLAKOWSKI, Gabrielle R. , METCALF, Andrew T. , MORENO, David A. , TANG, Tony P.

IPC分类号： C07D471/04 , C07D519/00

2.

发明公开
PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS 有权
标题翻译：用于治疗炎性或过度增殖性疾病合适Pyrimidocyclopentane

公开(公告)号：EP2170863A2

公开(公告)日：2010-04-07

申请号：EP08781337.4

申请日：2008-07-03

申请人： Array Biopharma, Inc. , Genentech, Inc.

发明人： BENCSIK, Josef , BLAKE, James, F. , GRAHAM, James, M. , HENTEMANN, Martin, F. , KALLAN, Nicholas, C. , MITCHELL, Ian, S. , SCHLACHTER, Stephen, T. , SPENCER, Keith, L. , XIAO, Dengming , XU, Rui , WELCH, Mike , LIANG, Jun , SAFINA, Brian, S.

IPC分类号： C07D401/12 , C07D403/12

CPC分类号： C07D403/12 , C07D401/12

摘要： The present invention provides compounds of Formula (I), including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

3.

发明授权
Pyrimido cyclopentanes useful for the treatment of inflammatory or hyperproliferative diseases 有权
标题翻译：用于治疗炎性或过度增殖性疾病合适Pyrimidocyclopentane

公开(公告)号：EP2170863B1

公开(公告)日：2015-09-02

申请号：EP08781337.4

申请日：2008-07-03

申请人： Array Biopharma, Inc. , Genentech, Inc.

发明人： BENCSIK, Josef , BLAKE, James, F. , GRAHAM, James, M. , HENTEMANN, Martin, F. , KALLAN, Nicholas, C. , MITCHELL, Ian, S. , SCHLACHTER, Stephen, T. , SPENCER, Keith, L. , XIAO, Dengming , XU, Rui , WELCH, Mike , LIANG, Jun , SAFINA, Brian, S.

IPC分类号： C07D401/12 , C07D403/12

CPC分类号： C07D403/12 , C07D401/12

4.

发明公开
RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF 审中-公开
标题翻译： RAF抗炎化合物及其使用方法

公开(公告)号：EP1902056A2

公开(公告)日：2008-03-26

申请号：EP06784432.4

申请日：2006-05-18

申请人： Array Biopharma, Inc.

发明人： LAIRD, Ellen , TOPALOV, Georg , LYSSIKATOS, Joseph, P. , WELCH, Mike , GRINA, Jonas , HANSEN, Josh , NEWHOUSE, BRAD

IPC分类号： C07D487/04

CPC分类号： C07D487/04

摘要： Compounds of Formula (I) are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using compounds of Formula (I), and stereoisomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.