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公开(公告)号:EP2739618B1
公开(公告)日:2015-09-16
申请号:EP12769775.3
申请日:2012-08-03
发明人: BLAKE, James, F. , CHEN, Huifen , CHICARELLI, Mark, Joseph , DEMEESE, Jason , GARREY, Rustam, Ferdinand , GAUDINO, John , GAZZARD, Lewis , KAUS, Robert J. , KINTZ, Samuel , MOHR, Peter J. , MORENO, David, A. , SCHWARZ, Jacob , SIEDEM, Christopher, S. , WALLACE, Eli, M.
IPC分类号: C07D405/14 , C07D403/12 , C07D413/14 , A61K31/517 , A61P35/00
CPC分类号: C07D405/14 , C07D403/12
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2.QUINAZOLINE COMPOUNDS AS SERINE/THREONINE KINASE INHIBITORS 有权
标题翻译: CHINAZOLINVERBINDUNGEN ALS SERIN- / THREONINKINASEHEMMER公开(公告)号:EP2739618A1
公开(公告)日:2014-06-11
申请号:EP12769775.3
申请日:2012-08-03
发明人: BLAKE, James, F. , CHEN, Huifen , CHICARELLI, Mark, Joseph , DEMEESE, Jason , GARREY, Rustam, Ferdinand , GAUDINO, John , GAZZARD, Lewis , KAUS, Robert J. , KINTZ, Samuel , MOHR, Peter J. , MORENO, David, A. , SCHWARZ, Jacob , SIEDEM, Christopher, S. , WALLACE, Eli, M.
IPC分类号: C07D403/12 , A61K31/517 , A61P35/00
CPC分类号: C07D405/14 , C07D403/12
摘要: Compounds having the formula (I) wherein R
1 , R
2 , R
3 and Ar as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.
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