公开(公告)号：EP3349761A1

公开(公告)日：2018-07-25

申请号：EP16847298.3

申请日：2016-09-15

申请人： Assembly Biosciences, Inc. ,  Indiana University Research and Technology Corporation

发明人： TURNER, William ,  ARNOLD, Lee, Daniel ,  MAAG, Hans ,  BURES, Mark

IPC分类号： A61K31/554 ,  C07D281/16 ,  C07D417/12

CPC分类号： C07D417/12 ,  A61K45/06 ,  A61P31/20 ,  C07D243/38 ,  C07D267/20 ,  C07D281/16 ,  C07D401/12 ,  C07D403/12 ,  C07D413/12 ,  C07D417/14 ,  C07D453/02 ,  C07D471/04

摘要： The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.

公开(公告)号：EP3512845A1

公开(公告)日：2019-07-24

申请号：EP17772267.5

申请日：2017-09-14

申请人： Assembly Biosciences, Inc.

发明人： TURNER, William ,  ARNOLD, Lee, Daniel ,  LI, Leping ,  BURES, Mark ,  HAYDAR, Simon ,  MAAG, Hans ,  BANNEN, Lynne

IPC分类号： C07D417/12 ,  C07D513/04 ,  C07D487/04

公开(公告)号：EP3782626A1

公开(公告)日：2021-02-24

申请号：EP20185808.1

申请日：2016-09-15

申请人： Assembly Biosciences, Inc. ,  Indiana University Research & Technology Corporation

发明人： TURNER, William ,  ARNOLD, Lee Daniel ,  MAAG, Hans ,  LI, Leping ,  BURES, Mark ,  HAYDAR, Simon ,  FRANCIS, Samson

IPC分类号： A61K31/554 ,  C07D281/16 ,  C07D417/12 ,  C07D417/14 ,  C07D413/12

摘要： The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.

公开(公告)号：EP3349580B1

公开(公告)日：2020-08-19

申请号：EP16847295.9

申请日：2016-09-15

申请人： Assembly Biosciences, Inc. ,  Indiana University Research and Technology Corporation

发明人： TURNER, William ,  ARNOLD, Lee, Daniel ,  MAAG, Hans ,  LI, Leping ,  BURES, Mark ,  HAYDAR, Simon ,  FRANCIS, Samson

IPC分类号： C07D401/12 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14 ,  C07D243/38 ,  C07D453/02 ,  C07D471/04 ,  C07D267/20 ,  C07D281/16 ,  A61K31/551 ,  A61K31/553 ,  A61K31/554 ,  A61P31/20

公开(公告)号：EP3349580A1

公开(公告)日：2018-07-25

申请号：EP16847295.9

申请日：2016-09-15

申请人： Assembly Biosciences, Inc. ,  Indiana University Research and Technology Corporation

发明人： TURNER, William ,  ARNOLD, Lee, Daniel ,  MAAG, Hans ,  LI, Leping ,  BURES, Mark ,  HAYDAR, Simon ,  FRANCIS, Samson

IPC分类号： A01N57/00

摘要： The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.