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公开(公告)号:EP2114941B1
公开(公告)日:2015-03-25
申请号:EP07848659.4
申请日:2007-12-21
发明人: BERDINI, Valerio , BESONG, Gilbert, Ebai , CALLAGHAN, Owen , CARR, Maria, Grazia , CONGREVE, Miles, Stuart , GILL, Adrian, Liam , GRIFFITHS-JONES, Charlotte, Mary , MADIN, Andrew , MURRAY, Christopher, William , NIJJAR, Rajdeep, Kaur , O'BRIEN, Michael, Alistair , PIKE, Andrew , SAXTY, Gordon , TAYLOR, Richard, David , VICKERSTAFFE, Emma
IPC分类号: C07D471/04 , C07D487/04 , A61K31/437 , A61K31/519 , A61P35/00
CPC分类号: C07D487/04 , A61K31/437 , C07D471/04
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公开(公告)号:EP2300465B1
公开(公告)日:2019-04-17
申请号:EP09761801.1
申请日:2009-06-12
发明人: BERDINI, Valerio , CARR, Maria, Grazia , CONGREVE, Miles, Stuart , FREDERICKSON, Martyn , GRIFFITHS-JONES, Charlotte, Mary , HAMLETT, Christopher, Charles, Frederick , MADIN, Andrew , MURRAY, Christopher, William , BENNING, Rajdeep Kaur , SAXTY, Gordon , VICKERSTAFFE, Emma , WOODHEAD, Andrew, James , WOODHEAD, Steven, John , FREYNE, Eddy, Jean, Edgard , GOVAERTS, Tom, Cornelis, Hortense , ANGIBAUD, Patrick, René , WILLIAMS, Brian, John
IPC分类号: C07D471/04 , C07D513/04 , A61P35/00 , A61K31/437 , A61K31/506 , A61K31/501 , A61K31/53 , A61K31/444 , A61K31/497 , A61K31/496 , A61K31/4545
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3.
公开(公告)号:EP2300465A1
公开(公告)日:2011-03-30
申请号:EP09761801.1
申请日:2009-06-12
发明人: BERDINI, Valerio , CARR, Maria, Grazia , CONGREVE, Miles, Stuart , FREDERICKSON, Martyn , GRIFFITHS-JONES, Charlotte, Mary , HAMLETT, Christopher, Charles, Frederick , MADIN, Andrew , MURRAY, Christopher, William , BENNING, Rajdeep Kaur , SAXTY, Gordon , VICKERSTAFFE, Emma , WOODHEAD, Andrew, James , WOODHEAD, Steven, John , FREYNE, Eddy, Jean, Edgard , GOVAERTS, Tom, Cornelis, Hortense , ANGIBAUD, Patrick, René , WILLIAMS, Brian, John
IPC分类号: C07D471/04 , C07D513/04 , A61P35/00 , A61K31/437 , A61K31/506 , A61K31/501 , A61K31/53 , A61K31/444 , A61K31/497 , A61K31/496 , A61K31/4545
CPC分类号: C07D471/04 , C07D513/04
摘要: The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising the compounds and to the use of the compounds in the treatment of diseases, e.g. cancer.
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4.
公开(公告)号:EP2121687A2
公开(公告)日:2009-11-25
申请号:EP07848681.8
申请日:2007-12-21
发明人: BERDINI, Valerio , BESONG, Gilbert Ebai , CALLAGHAN, Owen , CARR, Maria Grazia , CONGREVE, Miles Stuart , GILL, Adrian Liam , GRIFFITHS-JONES, Charlotte Mary , MADIN, Andrew , MURRAY, Christopher William , NIJJAR, Rajdeep Kaur , O'BRIEN, Michael Alistair , PIKE, Andrew , SAXTY, Gordon , TAYLOR, Richard David , VICKERSTAFFE, Emma
IPC分类号: C07D471/04 , C07D487/04 , A61K31/437 , A61P35/00
CPC分类号: C07D471/04 , C07D487/04
摘要: The invention relates to new bicyclic heterocyclic derivative compounds of Formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer. The compounds of Formula (I) are inhibitors of FGFR, VEGFR or PDGFR.
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5.
公开(公告)号:EP2121687B1
公开(公告)日:2015-10-14
申请号:EP07848681.8
申请日:2007-12-21
发明人: BERDINI, Valerio , BESONG, Gilbert Ebai , CALLAGHAN, Owen , CARR, Maria Grazia , CONGREVE, Miles Stuart , GILL, Adrian Liam , GRIFFITHS-JONES, Charlotte Mary , MADIN, Andrew , MURRAY, Christopher William , NIJJAR, Rajdeep Kaur , O'BRIEN, Michael Alistair , PIKE, Andrew , SAXTY, Gordon , TAYLOR, Richard David , VICKERSTAFFE, Emma
IPC分类号: C07D471/04 , C07D487/04 , A61K31/437 , A61P35/00
CPC分类号: C07D471/04 , C07D487/04
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公开(公告)号:EP2114941A1
公开(公告)日:2009-11-11
申请号:EP07848659.4
申请日:2007-12-21
发明人: BERDINI, Valerio , BESONG, Gilbert, Ebai , CALLAGHAN, Owen , CARR, Maria, Grazia , CONGREVE, Miles, Stuart , GILL, Adrian, Liam , GRIFFITHS-JONES, Charlotte, Mary , MADIN, Andrew , MURRAY, Christopher, William , NIJJAR, Rajdeep, Kaur , O'BRIEN, Michael, Alistair , PIKE, Andrew , SAXTY, Gordon , TAYLOR, Richard, David , VICKERSTAFFE, Emma
IPC分类号: C07D471/04 , C07D487/04 , A61K31/437 , A61K31/519 , A61P35/00
CPC分类号: C07D487/04 , A61K31/437 , C07D471/04
摘要: The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
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