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1.发明授权CRYSTALLINE SOLVATES OF (1S)-1,5-ANHYDRO-1-C-(3-((PHENYL) METHYL) PHENYL)-D-GLUCITOL DERIVATIVES WITH ALCOHOLS AS SGLT2 INHIBITORS FOR THE TREATMENT OF DIABETES 有权（1S）-1,5-壬基-1-C-（3 - （（苯基）甲基）苯基）-D-葡萄糖醇衍生物麻醉碱性醇ALS SGLT2-抑制剂ZUR BEHANDLUNG VON糖尿病
公开(公告)号：EP2069374B1
公开(公告)日：2014-07-30
申请号：EP07784499.1
申请日：2007-06-21
申请人： AstraZeneca AB
发明人： GOUGOUTAS, Jack, Z. , LOBINGER, Hildegard , RAMAKRISHNAN, Srividya , DESHPANDE, Prashant, P. , BIEN, Jeffrey, T. , LAI, Chiajen , WANG, Chenchi , RIEBEL, Peter , GROSSO, John, Anthony , NIRSCHL, Alexandra, A. , SINGH, Janak , DIMARCO, John, D.
CPC分类号： C07H15/207 , A61K31/7034 , A61K45/06 , A61P3/10 , C07H7/04
摘要： The present invention relates to physical crystal structures of a compound of the formula I: wherein R 1 , R 2 , R 2a , R 3 and R 4 are as defined herein, especially pharmaceutical compositions containing structures of compound I or II, processes for preparing same, intermediates used in preparing same, and methods of treating diseases such as diabetes using such structures.
摘要翻译： 本发明涉及式I化合物的物理结晶结构：其中R 1，R 2，R 2a，R 3和R 4如本文所定义，特别是含有化合物I或II结构的药物组合物，制备方法 相同的，制备相同的中间体，以及使用这种结构治疗糖尿病等疾病的方法。
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