专利检索 ap:("AstraZeneca AB") AND inv:"LINDSJÖ, Martin" 第 1 页

1.

发明公开
2-PYRIDONE COMPOUNDS USED AS INHIBITORS OF NEUTROPHIL ELASTASE 审中-公开
标题翻译： 2-吡啶酮ALS抑制剂嗜中性粒细胞

公开(公告)号：EP2483244A1

公开(公告)日：2012-08-08

申请号：EP10760396.1

申请日：2010-09-22

申请人： AstraZeneca AB

发明人： MURUGAN, Andiappan , ASHTON, Mark , BERGSTROM, Lena, Kristina , KRISTOFFERSSON, Anna , LINDSJÖ, Martin , SJÖ, Peter, Olof , MEIGH, Jon

IPC分类号： C07D213/64 , C07D401/04 , C07D401/14 , C07D403/04 , A61K31/4439 , A61K31/497 , A61P29/00

CPC分类号： C07D401/14 , C07D213/64 , C07D401/04 , C07D403/04

摘要： The invention provides compounds of formula (I) wherein R
1 , R
3 , R
4 , R
5 , R
6 , R
7 , L, X and Y are as defined in the specification; together with processes and intermediates for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of human neutrophil elastase.

2.

发明公开
SOME 2-PYRAZINONE DERIVATIVES AND THEIR USE AS INHIBITORS OF NEUTROPHILE ELASTASE 审中-公开
标题翻译： 2 PYRAZINONDERIVATE及其作为抑制剂中性粒细胞弹性

公开(公告)号：EP2217591A1

公开(公告)日：2010-08-18

申请号：EP08847756.7

申请日：2008-11-05

申请人： AstraZeneca AB

发明人： AINGE, Debra , CHAPMAN, David , LINDSJÖ, Martin , LÖNN, Hans , LUNDKVIST, Michael , MUNCK AF ROSENSCHÖLD, Magnus , NIKITIDIS, Antonios , PAVEY, John

IPC分类号： C07D403/04 , A61K31/497 , A61P1/04 , A61P11/00 , A61P19/00 , C07D401/14

CPC分类号： C07D401/14 , C07D403/04

摘要： The invention provides certain novel 6-heteroaryl-5-methyl-3- oxo-4- [3 (trif luoromethyl) phenyl] -3,4-dihydropyrazine-2- carboxamide derivatives and pharmaceutically acceptable salts thereof and particular Forms thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitord of human neutrophil elastase.