专利检索 ap:("AstraZeneca AB" OR "NPS PHARMACEUTICALS, INC.") AND inv:"MCLEOD, Donald" 第 1 页

1.

发明公开
ADDITIONAL HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS 有权
标题翻译：更多的多环化合物及其作为METABO谷氨酸受体的拮抗剂

公开(公告)号：EP1723144A1

公开(公告)日：2006-11-22

申请号：EP05802855.6

申请日：2005-02-15

申请人： AstraZeneca AB , NPS PHARMACEUTICALS, INC.

发明人： EDWARDS, Louise , ISAAC, Methvin , JOHANSSON, Martin , KERS, Annika , MALMBERG, Johan , MCLEOD, Donald , MINIDIS, Alexander , STAAF, Karin , SLASSI, Abdelmalik , STEFANAC, Tomislav , STORMANN, Thomas , WENSBO, David , XIN, Tao , ARORA, Jalaj

IPC分类号： C07D413/12 , C07D413/14 , C07D487/04 , A61K31/519 , A61P25/28 , C07D413/06

CPC分类号： C07D487/04 , C07D413/06 , C07D413/12 , C07D413/14

摘要： The present invention relates to new compounds of formula (I), to pharmaceutical formulations containing the compounds, and to the use of the compounds in the prevention and/or treatment of mGluR5 receptor-mediated disorders.

2.

发明授权
ADDITIONAL HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS 有权
标题翻译：更多的多环化合物及其作为METABO谷氨酸受体的拮抗剂

公开(公告)号：EP1723144B1

公开(公告)日：2010-10-06

申请号：EP05802855.6

申请日：2005-02-15

申请人： AstraZeneca AB

发明人： EDWARDS, Louise , ISAAC, Methvin , JOHANSSON, Martin , KERS, Annika , MALMBERG, Johan , MCLEOD, Donald , MINIDIS, Alexander , STAAF, Karin , SLASSI, Abdelmalik , STEFANAC, Tomislav , STORMANN, Thomas , WENSBO, David , XIN, Tao , ARORA, Jalaj

IPC分类号： C07D413/12 , C07D413/14 , C07D487/04 , A61K31/519 , A61P25/28 , C07D413/06

CPC分类号： C07D487/04 , C07D413/06 , C07D413/12 , C07D413/14

摘要： The present invention relates to new compounds of formula (I), to pharmaceutical formulations containing the compounds, and to the use of the compounds in the prevention and/or treatment of mGluR5 receptor-mediated disorders.

3.

发明公开
SUBSTITUTED PIPERAZINES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS 审中-公开
标题翻译：取代的哌嗪热带METABO谷氨酸受体拮抗剂

公开(公告)号：EP1919901A1

公开(公告)日：2008-05-14

申请号：EP06789371.9

申请日：2006-08-04

申请人： AstraZeneca AB

发明人： EDWARDS, Louise , SLASSI, Abdelmalik , ISAAC, Methvin , MCLEOD, Donald , XIN, Tao

IPC分类号： C07D401/12 , C07D403/12 , C07D413/12 , A61K31/4545 , A61K31/455 , A61K31/497 , A61K31/506 , A61P25/00 , A61P1/00

CPC分类号： C07D413/12 , C07D261/08 , C07D401/12 , C07D403/12

摘要： The invention relates to compounds of formula I or pharmaceutically acceptable salts or solvates thereof: where Ar1, Ar2, Hy, L, R1, m and n are as defined in the description. The invention also includes pharmaceutical compositions and uses thereof, processes for making the compounds, as well as methods for the medical treatment of mGluR5-mediated disorders.