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1.发明公开POLYHETEROCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS 审中-公开聚杂环化合物及其作为METABO谷氨酸受体的拮抗剂
公开(公告)号：EP1716143A1
公开(公告)日：2006-11-02
申请号：EP05713792.9
申请日：2005-02-17
发明人： ARORA, Jalaj , EDWARDS, Louise, NPS Allelix Corp. , ISAAC, Methvin, NPS Allelix Corp. , KERS, Annika, AstraZeneca R & D Headquarters , STAAF, Karin, AstraZeneca R & D Headquarters , SLASSI, Abdelmalik, NPS Allelix Corp. , STEFANAC, Tomislav, NPS Allelix Corp. , WENSBO, David, AstraZeneca R & D Headquarters , XIN, Tao , HOLM, Björn
IPC分类号： C07D413/14 , A61K31/4545 , A61P25/00 , A61K31/5377 , A61K31/496 , C07D401/14
CPC分类号： C07D401/04 , C07D401/14 , C07D403/14 , C07D413/04 , C07D413/14
摘要： The present invention relates to new compounds of formula (I), wherein P, Q, X1, X2, X3, X4, X5, X6, R1, R2, R3, m, n, and p are as defined as in formula (I), or salts, or hydrates thereof, processes for their preparation and new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy.
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2.发明公开TETRAZOLE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONITS 有权四唑及其作为METABO谷氨酸受体的拮抗剂
公开(公告)号：EP1716125A1
公开(公告)日：2006-11-02
申请号：EP05713793.7
申请日：2005-02-17
发明人： JOHANSSON, Martin, AstraZeneca R & D Headquarters , MINIDIS, Alexander, AstraZeneca R & D Headquarters , STAAF, Karin, AstraZeneca R & D Headquarters , WENSBO, David, AstraZeneca R & D Headquarters , MCLEOD, Donald, NPS Pharmaceuticals, Inc. , EDWARDS, Louise, NPS Allelix Corp. , ISAAC, Methvin, NPS Allelix Corp. , O'BRIEN, Anne, NPS Allelix Corp. , SLASSI, Abdelmalik, NPS Allelix Corp. , XIN, Tao
IPC分类号： C07D257/04 , C07D401/14 , C07D403/12 , C07D401/12 , C07D487/04 , C07D403/06 , A61K31/41 , A61K31/4439 , A61K31/496 , A61K31/497 , A61P25/00
CPC分类号： C07D257/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D471/04 , C07D487/04
摘要： The present invention relates to new compounds of formula I, wherein P, Q, X1, X2, X3, X4, R1, R2, m and p, are as defined as in formula I, or salts, solvates or solvated salts thereof, processes for their preparation and new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds, and to the use of said compounds in therapy.
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3.发明授权TETRAZOLE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONITS 有权四唑及其作为METABO谷氨酸受体的拮抗剂
公开(公告)号：EP1716125B1
公开(公告)日：2013-06-19
申请号：EP05713793.7
申请日：2005-02-17
申请人： AstraZeneca AB
发明人： JOHANSSON, Martin, AstraZeneca R & D Headquarters , MINIDIS, Alexander, AstraZeneca R & D Headquarters , STAAF, Karin, AstraZeneca R & D Headquarters , WENSBO, David, AstraZeneca R & D Headquarters , MCLEOD, Donald, NPS Pharmaceuticals, Inc. , EDWARDS, Louise, NPS Allelix Corp. , ISAAC, Methvin, NPS Allelix Corp. , O'BRIEN, Anne, NPS Allelix Corp. , SLASSI, Abdelmalik, NPS Allelix Corp. , XIN, Tao
IPC分类号： C07D257/04 , C07D401/14 , C07D403/12 , C07D401/12 , C07D487/04 , C07D403/06 , A61K31/41 , A61K31/4439 , A61K31/496 , A61K31/497 , A61P25/00
CPC分类号： C07D257/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D471/04 , C07D487/04
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