公开(公告)号：EP1581505A1

公开(公告)日：2005-10-05

申请号：EP03775372.0

申请日：2003-11-19

申请人： Aventis Pharma Deutschland GmbH

发明人： HOELDER, Swen ,  NAUMANN, Thorsten ,  SCHOENAFINGER, Karl ,  WILL, David, William ,  MATTER, Hans ,  MUELLER, Guenter ,  LE SUISSE, Dominique ,  BAUDOIN, Bernard ,  ROONEY, Thomas ,  HALLEY, Franck ,  TIRABOSCHI, Gilles

IPC分类号： C07D237/24 ,  C07D401/04 ,  C07D401/14 ,  C07D413/14 ,  C07D401/12 ,  C07D403/04 ,  C07D405/14 ,  C07D409/14 ,  C07D409/04 ,  C07D413/04 ,  C07D513/04 ,  C07D417/04 ,  A61K31/50 ,  A61P25/00

CPC分类号： C07D401/04 ,  C07D237/14 ,  C07D237/24 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D405/04 ,  C07D405/14 ,  C07D409/04 ,  C07D409/14 ,  C07D413/04 ,  C07D417/14 ,  C07D513/04 ,  Y02P20/582

摘要： The present invention relates to novel pyridazinone derivatives of the general formula (I) wherein A is A1 or A2; R is unsubstituted or at least monosubstituted C1-C10-alkyl, aryl, aryl (C1-C10-alkyl)-, heteroaryl, heteroaryl-(C1-C10-­alkyl)-, heterocyclyl, heterocyclyl-(C1-C10-alkyl)-, C3-C10-cycloalkyl, polycycloalkyl, C2-C10 alkenyl or C2-C10-alkinyl and Ar is unsubstituted or at least monosubstituted aryl or heteroaryl.