公开(公告)号：EP0763116B2

公开(公告)日：2008-04-23

申请号：EP95920972.7

申请日：1995-05-22

申请人： Aventis Pharma S.A. ,  THE UNIVERSITY OF BRITISH COLUMBIA

发明人： BENOIT, Patrick ,  DENEFLE, Patrice ,  PERRICAUDET, Michel ,  HAYDEN, Michael R. ,  LEWIS, Marion Elizabeth Suzanne

IPC分类号： C12N15/55 ,  A61K38/43 ,  C12N15/86 ,  C12N5/10 ,  A61K48/00 ,  A61K9/22 ,  C12N7/01 ,  C12R1/91

CPC分类号： A61K48/005 ,  A61K38/00 ,  A61K38/465 ,  A61K48/00 ,  A61K2039/51 ,  C12N9/20 ,  C12N15/86 ,  C12N2710/10343 ,  C12Y301/01034

摘要： Recombinant viruses comprising a heterologous DNA sequence coding for a lipase involved in lipoprotein metabolism. The invention also concerns the preparation and use in therapy of said recombinant viruses, especially for the treatment or prevention of dyslipoproteinemia-related pathologies.

公开(公告)号：EP0763116B1

公开(公告)日：2003-09-03

申请号：EP95920972.7

申请日：1995-05-22

申请人： Aventis Pharma S.A.

发明人： BENOIT, Patrick ,  DENEFLE, Patrice ,  PERRICAUDET, Michel ,  HAYDEN, Michael R. ,  LEWIS, Marion Elizabeth Suzanne

IPC分类号： C12N15/55 ,  A61K38/43 ,  C12N15/86 ,  C12N5/10 ,  A61K48/00 ,  A61K9/22 ,  C12N7/01

CPC分类号： A61K48/005 ,  A61K38/00 ,  A61K38/465 ,  A61K48/00 ,  A61K2039/51 ,  C12N9/20 ,  C12N15/86 ,  C12N2710/10343 ,  C12Y301/01034

摘要： Recombinant viruses comprising a heterologous DNA sequence coding for a lipase involved in lipoprotein metabolism. The invention also concerns the preparation and use in therapy of said recombinant viruses, especially for the treatment or prevention of dyslipoproteinemia-related pathologies.