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1.发明授权USE OF THIAZOLOBENZOHETEROCYCLES FOR TREATING MULTIPLE SCLEROSIS 有权THIAZOLBENZO-HETEROCYCLENFÜR的使用的治疗多发性硬化症
公开(公告)号：EP1585525B1
公开(公告)日：2010-11-17
申请号：EP03814050.5
申请日：2003-12-16
发明人： ZHU, Bin , WETTSTEIN, Joseph , PETTY, Margaret
CPC分类号： A61K31/538 , A61K31/542 , A61K31/55 , A61K31/553 , A61K31/554
摘要： The invention relates to the use of compound of Formula (I) in treating patients for inflammatory or neuropathic pain as well as various symptoms of multiple schlerosis.
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2.发明公开A MOUSE UNABLE TO EXPRESS FUNCTIONAL ALPHA-4 INTEGRIN PROTEIN, AND METHODS FOR ASSAYING COMPOUNDS OR AGENTS FOR ALPHA-4 INTEGRIN PROTEIN ANTAGONIST ACTIVITY AND A GENETIC MARKER FOR EVALUATING EFFICACY OF MODULATORS OF SIGNALING ACTIVITY OF A VLA-4 RECEPTOR 审中-公开METHOD FOR化合物或物质对VLA-4受体蛋白拮抗剂活性试验用遗传标记
公开(公告)号：EP1406997A2
公开(公告)日：2004-04-14
申请号：EP02741981.1
申请日：2002-06-07
发明人： WASEL-NIELEN, Monika , KIRSCHBAUM, Bernhard , FOSTER, Martyn , POLITES, Gregory , KHORKOVA, Olga , ZHU, Bin
IPC分类号： C12N1/00
CPC分类号： C12N15/8509 , A01K67/0276 , A01K2217/072 , A01K2217/075 , A01K2227/105 , A01K2267/03
摘要： Provided herein is a mouse that is unable to express functional alpha-4-integrin protein, and methods for assaying agents for alpha-4 integrin antagonist activity, as well as genetic markers for analyzing the efficacy of VLA-4 modulators, and particularly antagonists.
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3.发明公开USE OF THIAZOLOBENZOHETEROCYCLES FOR TREATING MULTIPLE SCLEROSIS 有权THIAZOLBENZO-HETEROCYCLENFÜR的使用的治疗多发性硬化症
公开(公告)号：EP1585525A1
公开(公告)日：2005-10-19
申请号：EP03814050.5
申请日：2003-12-16
发明人： ZHU, Bin , WETTSTEIN, Joseph , PETTY, Margaret
CPC分类号： A61K31/538 , A61K31/542 , A61K31/55 , A61K31/553 , A61K31/554
摘要： The invention relates to the use of compound of Formula (I) in treating patients for inflammatory or neuropathic pain as well as various symptoms of multiple schlerosis.
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