-
1.Processes for the preparation of (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-Fluorophenyl)ethyl]-4-piperidinemethanol 审中-公开
标题翻译: (2,3-二甲氧基苯基)-1- [2-(4-氟苯基)乙基] -4-哌啶 - 甲为(R)-G(A)的制备方法公开(公告)号:EP1736469A3
公开(公告)日:2010-06-09
申请号:EP06016487.8
申请日:1999-03-11
发明人: Bina, Alan, G. , Daugs, Edward, D. , Evans, Jonathan, C. , Flemming, Hans-Wolfram , Guillamot, Gerard , Hawtorne, Robert, A. , Hilpert, Thomas, H.E. , Hitt, James, E. , King, Chi-Hsin, R. , Koek, Johannes, N. , Laskovics, Frederick, M. , Lefler, John, M. , Margolin, Alexey, L. , Minish, Sharon, K. , Ortyl, Thomas, T. , Rajewski, Lian, G. , Sack, Marvin, J. , Skultety, Paul, F. , Stoltz-Dunn, Sandra, K. , Tigner, Alonzo, L. , Tomlinson, Ian, A.
IPC分类号: C07D211/22 , C07D211/32
CPC分类号: C07D211/32 , C07D211/22
摘要: The present invention provides various processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol. These processes may be characterized by the following scheme:
-
2.Processes for the preparation of (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-Fluorophenyl)ethyl]-4-piperidinemethanol 审中-公开
标题翻译: (A) - (2,3-二甲氧基苯基)-1- [2-(4-氟苯基)乙基] -4-哌啶甲醇公开(公告)号:EP1736469A2
公开(公告)日:2006-12-27
申请号:EP06016487.8
申请日:1999-03-11
发明人: Bina, Alan, G. , Daugs, Edward, D. , Evans, Jonathan, C. , Flemming, Hans-Wolfram , Guillamot, Gerard , Hawtorne, Robert, A. , Hilpert, Thomas, H.E. , Hitt, James, E. , King, Chi-Hsin, R. , Koek, Johannes, N. , Laskovics, Frederick, M. , Lefler, John, M. , Margolin, Alexey, L. , Minish, Sharon, K. , Ortyl, Thomas, T. , Rajewski, Lian, G. , Sack, Marvin, J. , Skultety, Paul, F. , Stoltz-Dunn, Sandra, K. , Tigner, Alonzo, L. , Tomlinson, Ian, A.
IPC分类号: C07D211/22 , C07D211/32
CPC分类号: C07D211/32 , C07D211/22
摘要: The present invention provides various processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol. These processes may be characterized by the following scheme:
摘要翻译: 本发明提供制备(R) - (2,3-二甲氧基苯基)-1- [2-(4-氟苯基)乙基] -4-哌啶甲醇的各种方法。 这些过程可以通过以下方案来表征:
-