公开(公告)号：EP1985298A1

公开(公告)日：2008-10-29

申请号：EP07008357.1

申请日：2007-04-24

申请人： Azad Pharma AG

发明人： Carli, Fabio ,  Baronian, Mihran ,  Schmid, Rene

IPC分类号： A61K31/557 ,  A61K9/00 ,  A61K47/10 ,  A61K47/26 ,  A61K47/44

CPC分类号： A61K9/0048 ,  A61K9/107 ,  A61K31/557 ,  A61K31/5575 ,  A61K47/14 ,  A61K47/26 ,  A61K47/44 ,  Y02A50/465

摘要： The present invention refers to an oil-in-water emulsion for ophthalmic application comprising at least one prostaglandin as active agent and a surfactant component comprising a combination of at least two non-ionic surfactants. The emulsion is suitable for medical applications, particularly for the treatment of glaucoma, and has an increased chemical stability of the prostaglandin active agent so to allow long-term storage also at room temperature.

摘要翻译： 本发明涉及用于眼科应用的水包油乳液，其包含至少一种作为活性剂的前列腺素和包含至少两种非离子表面活性剂的组合的表面活性剂组分。 该乳剂适用于医疗应用，特别是用于治疗青光眼，并且具有增加的前列腺素活性剂的化学稳定性，从而允许在室温下长期储存。