公开(公告)号：EP4442249A1

公开(公告)日：2024-10-09

申请号：EP23167083.7

申请日：2023-04-06

申请人： B. Braun Melsungen AG

发明人： Janas, Christine ,  Porredon Guarch, Constanca ,  Ziller, Antje ,  Bauer, Marius

IPC分类号： A61K9/00 ,  A61K31/5517 ,  A61K47/10 ,  A61K47/32 ,  A61K47/38 ,  A61K47/40 ,  A61P25/08 ,  A61P25/20 ,  A61P25/22

CPC分类号： A61K31/5517 ,  A61K9/0056 ,  A61K47/40 ,  A61K47/38 ,  A61K47/32 ,  A61K47/10 ,  A61P25/08 ,  A61K9/006

摘要： The present invention relates to a unit dosage composition comprising midazolam or a pharmaceutically acceptable salt thereof, a cyclodextrin, and at least one matrix material, as well as to the use of said unit dosage composition in medicine and therapy, in particular in the treatment of febrile seizure, epileptic seizure, such as status epilepticus, fear, such as preoperative anxiolysis to reduce fear, and/or agitation, such as agitation prior to surgery.