Lyase enzymes, nucleic acids encoding them and methods for making and using them
    1.
    发明公开
    Lyase enzymes, nucleic acids encoding them and methods for making and using them 审中-公开
    Lyaseenzyme,编码它们的核酸,以及制备和使用其的方法

    公开(公告)号:EP2886658A1

    公开(公告)日:2015-06-24

    申请号:EP15150156.6

    申请日:2006-03-10

    申请人: BASF Enzymes LLC

    摘要: This invention provides polypeptides having lyase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides having ammonia lyase activity, eg phenylalanine ammonia lyase, tyrosine ammonia lyase and/or histidine ammonia lyase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts.

    摘要翻译: 本发明提供具有裂合酶活性的多肽,多核苷酸编码所述多肽的合成,以及制备和使用这些多核苷酸和多肽的方法。 在一个方面,本发明涉及多肽,其具有氨解酶活性,例如,苯丙氨酸氨裂解酶,酪氨酸脱氨酶和/或组氨酸脱氨酶的活性,包括热电表和耐热活性,多核苷酸编码合成的酶,以及制备和使用这些多核苷酸和 多肽。 本发明的多肽可以在多种药物,农业和工业环境中使用。