VERFAHREN ZUR HERSTELLUNG M- ODER P-SUBSTITUIERTER PHENYLALKANOLE DURCH ALKYLIERUNG
    8.
    发明公开
    VERFAHREN ZUR HERSTELLUNG M- ODER P-SUBSTITUIERTER PHENYLALKANOLE DURCH ALKYLIERUNG 有权
    过程为生产或M-P-取代的苯基链烷醇烷基化

    公开(公告)号:EP2490992A1

    公开(公告)日:2012-08-29

    申请号:EP10765445.1

    申请日:2010-10-14

    Applicant: BASF SE

    CPC classification number: C07C29/32 C07C29/56 C07C45/29 C07C33/20 C07C47/228

    Abstract: The invention provides a process for preparing m- or p-substituted phenylalkanols of the formula (I) in which R
    1 is m- or p-bonded to the phenyl ring and is C
    1 -C
    5 -alkyl, and R
    2 , R
    3, R
    4 and R
    5 are each independently hydrogen or methyl, which is characterized in that an unsubstituted phenylalkanol of the formula (II) in which R
    2 , R
    3 , R
    4 and R
    5 are each as defined for formula (I) is alkylated together with a C
    1 -C
    5 -alkyl halide of the formula (III) R
    1 Hal (III), in which R
    1 is as defined for formula (I) and Hal is halogen, in the presence of a Friedel-Crafts catalyst, to give an m- or p-alkyl-substituted phenylalkanol of the formula (I), then the reaction mixture is worked up and the desired m- or p-alkyl-substituted phenylalkanol of the formula (I) is removed, the remaining by-products formed are returned to the reaction mixture and these are isomerized in the presence of a Friedel-Crafts catalyst to give the desired m- or p- alkyl-substituted phenylalkanol. The m- or p-alkyl-substituted phenylalkanols of the formula (I) can be used to form, by oxidation or dehydrogenation, as products of value, the corresponding aldehydes, which are of interest as fragrances and aroma chemicals.

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