公开(公告)号：EP2158185B1

公开(公告)日：2011-08-17

申请号：EP08761025.9

申请日：2008-06-13

Applicant: BASF SE

Inventor： NETT, Markus ,  GROTE, Thomas ,  LOHMANN, Jan Klaas ,  DIETZ, Jochen ,  SMIDT, Sebastian Peer ,  RACK, Michael ,  ZIERKE, Thomas

IPC: C07D231/12 ,  C07D231/14

CPC classification number: C07D231/12 ,  C07D231/14

Abstract: The invention relates to a method for producing 3-difluoromethyl-substituted pyrazole compounds of formula (I), wherein R1 represents H, halogen, nitro, C1-C8 alkyl, C1-C8 haloalkyl, C3-C8 cycloalkyl, phenyl, naphthyl, hetaryl, cyano, -C(=O)-OR1a, -C(=O)-NR1bR1c, -C(=O)-SR1d or -C(=S)-SR1e; R2 represents H, C1-C4 alkyl, benzyl or phenyl; R3 represents H, halogen, C1-C8 alkoxy, C1-C8 haloalkoxy, C3-C8 cycloalkoxy, C2-C8 alkenyloxy, C1-C8 alkylthio, C1-C8 haloalkylthio, C3-C8 cycloalkylthio or C2-C8 alkenylthio; to compounds of formula (II.a) or (II.b), wherein R1 and R3 have one of the above definitions; R4 represents halogen, -OR4a, -SR4a , -O-SO2-R4a or a group -NR4bR4c; R5 and R6 represent C1-C8 alkyl, C1-C8 haloalkyl, C3-C8 cycloalkyl, benzyl or phenyl or together with the nitrogen atom to which they are bound represent a 3- to 8-membered heterocycle; to Lewis acid adducts of compounds of formula (II.b); to the use of compounds of formula (II.a) or (II.b) and of the Lewis acid adducts thereof for producing compounds of formula (I) or (VI); and to a method for converting said compounds to the corresponding 3-difluoromethylpyrazole-4-yl carboxylic acids.

公开(公告)号：EP2513067A1

公开(公告)日：2012-10-24

申请号：EP10790782.6

申请日：2010-12-13

Applicant: BASF SE

Inventor： RENNER, Jens ,  DIETZ, Jochen ,  GROTE, Thomas ,  GEBHARDT, Joachim ,  NETT, Markus ,  KEIL, Michael

IPC: C07D249/12

CPC classification number: C07D249/12

Abstract: The present invention relates to a new process for the preparation of substituted thio-triazolo groups of the general formula (I) wherein the variables have the meanings as given in the claims and the description.

公开(公告)号：EP2158185A2

公开(公告)日：2010-03-03

申请号：EP08761025.9

申请日：2008-06-13

Applicant: BASF SE

Inventor： NETT, Markus ,  GROTE, Thomas ,  LOHMANN, Jan Klaas ,  DIETZ, Jochen ,  SMIDT, Sebastian Peer ,  RACK, Michael ,  ZIERKE, Thomas

IPC: C07D231/12 ,  C07D231/14

CPC classification number: C07D231/12 ,  C07D231/14

Abstract: The invention relates to a method for producing 3-difluoromethyl-substituted pyrazole compounds of formula (I), wherein R1 represents H, halogen, nitro, C1-C8 alkyl, C1-C8 haloalkyl, C3-C8 cycloalkyl, phenyl, naphthyl, hetaryl, cyano, -C(=O)-OR1a, -C(=O)-NR1bR1c, -C(=O)-SR1d or -C(=S)-SR1e; R2 represents H, C1-C4 alkyl, benzyl or phenyl; R3 represents H, halogen, C1-C8 alkoxy, C1-C8 haloalkoxy, C3-C8 cycloalkoxy, C2-C8 alkenyloxy, C1-C8 alkylthio, C1-C8 haloalkylthio, C3-C8 cycloalkylthio or C2-C8 alkenylthio; to compounds of formula (II.a) or (II.b), wherein R1 and R3 have one of the above definitions; R4 represents halogen, -OR4a, -SR4a , -O-SO2-R4a or a group -NR4bR4c; R5 and R6 represent C1-C8 alkyl, C1-C8 haloalkyl, C3-C8 cycloalkyl, benzyl or phenyl or together with the nitrogen atom to which they are bound represent a 3- to 8-membered heterocycle; to Lewis acid adducts of compounds of formula (II.b); to the use of compounds of formula (II.a) or (II.b) and of the Lewis acid adducts thereof for producing compounds of formula (I) or (VI); and to a method for converting said compounds to the corresponding 3-difluoromethylpyrazole-4-yl carboxylic acids.

公开(公告)号：EP3743408A1

公开(公告)日：2020-12-02

申请号：EP19701787.4

申请日：2019-01-14

Applicant: BASF SE

Inventor： MUELLER, Bernd ,  RACK, Michael ,  SEET, Michael ,  ESCRIBANO CUESTA, Ana ,  LOHMANN, Jan Klaas ,  RUDOLF, Georg Christoph ,  NETT, Markus ,  HOFFMANN, Rainer

IPC: C07D217/26 ,  C07D401/04