公开(公告)号：EP0042408A4

公开(公告)日：1982-04-29

申请号：EP81900238

申请日：1980-11-28

申请人： BAXTER TRAVENOL LAB

发明人： RADLICK PHILLIP C

IPC分类号： B01J23/40 ,  C07B61/00 ,  C07C27/00 ,  C07C29/136 ,  C07C29/143 ,  C07C29/145 ,  C07C31/38 ,  C07C31/40 ,  C07C41/00 ,  C07C43/12 ,  C07C45/29 ,  C07C45/32 ,  C07C45/63 ,  C07C67/00 ,  C07C43/02 ,  C07C31/34 ,  C07C45/35

CPC分类号： C07C29/145 ,  C07C41/01 ,  C07C45/29 ,  C07C45/32 ,  C07C45/63 ,  C07C31/38 ,  C07C43/123 ,  C07C49/08 ,  C07C49/167

摘要： Hexafluoropropylene may be conventionally oxidized to form an impure mixture comprising hexafluoroacetone and residual hexafluoropropylene, which materials are separable only with difficulty. The impure mixture may be subjected to reducing conditions to hydrogenate the hexafluoroacetone to a hexafluoroisopropanol product, which product is easily separable from the hexafluoropropylene impurity, which impurity may be recycled for further oxygenation and production of the acetone. Alternatively, hexafluoroisopropanol may be conventionally made from hexachloroacetone to form an impure mixture of hexafluoroacetone and HF. When this impure mixture is hydrogenated, the resulting hexafluoroisopropanol, mixed with hydrogen fluoride, is formed. Either of these alcohol products may be reacted with hydrogen fluoride and a formaldehyde to obtain a fluoromethyl-1,1,1,-3,3,3-hexafluoroisopropyl ether, which is a useful anesthetic.