专利检索 ap:("BIOCON RES LTD") AND inv:"SRIVASTAVA RUCHIKA" 第 1 页

1.

发明公开
A METHOD FOR REDUCING HETEROGENEITY OF ANTIBODIES AND A PROCESS OF PRODUCING THE ANTIBODIES THEREOF 有权
标题翻译：降低抗体异质性的方法及其抗体生产方法

公开(公告)号：EP2702164A4

公开(公告)日：2014-12-17

申请号：EP12777325

申请日：2012-04-27

申请人： BIOCON RES LTD , MYLAN GMBH

发明人： SRIVASTAVA RUCHIKA , HEMDEV SNEHA LAKSHMANDAS , BHATNAGAR ANKUR , DESAN SARAVANAN , GOEL ANUJ , IYER HARISH

IPC分类号： C12P21/08 , A61K39/395 , C07K16/00

CPC分类号： C12P21/00 , A61K39/39591 , C07K16/00 , C07K2317/14

2.

发明公开
METHODS FOR REDUCING ACCUMULATION OF LACTATE DURING CULTURING AND METHOD FOR PRODUCING POLYPEPTIDE 有权
标题翻译：减少培养期间乳酸盐累积的方法和生产多肽的方法

公开(公告)号：EP2702143A4

公开(公告)日：2014-12-17

申请号：EP12776121

申请日：2012-04-27

申请人： BIOCON RES LTD

发明人： SRIVASTAVA RUCHIKA , HEMDEV SNEHA LAKSHMANDAS , BHATNAGAR ANKUR , DESAN SARAVANAN , GOEL ANUJ , IYER HARISH , RAJA VANA , RAO LAVANYA

IPC分类号： C12N5/02 , C07K16/28 , C12N1/38 , C12N5/00 , C12P21/00 , C12P21/08

CPC分类号： C12P21/00 , C07K16/2863 , C07K16/2866 , C07K16/2896 , C12N5/0018 , C12N2500/10

摘要： The present disclosure relates to methods of decreasing lactate production in cell culture using divalent transitional metallic salts. The present disclosure also relates to a method of producing polypeptide by adding divalent transitional metallic salt to the cell culture medium for reducing lactate accumulation followed by fermenting and recovering the polypeptide.