摘要:
The invention relates to urethane-protected amino acid-N-carboxyanhydride and N-thiocarboxyanhydride compounds which are useful in peptide, polypeptide, and protein synthesis. Disclosed herein is the preparation and use of these novel compounds.
摘要:
Metabolically-acceptable, surgical adhesives are prepared from polyisocyanates having structural formula (I), wherein R is a polyvalent aliphatic radical of about 1 to 10 carbon atoms or a polyvalent aromatic radical of 6 to about 24 carbon atoms; A is C, S or P; Z is O or S; y is 1 when A is C or P, and 2 when A is S; n is 1 or 2; p is at least 1; q is 0 or 1, with the proviso that when A is carbon or sulfur, q is 0; r is 0 or 1, with the proviso that when A is carbon or sulfur, r is 0; X is a residue of an organic compound having active hydrogen-containing groups; and X' is a residue of an organic compound having at least 1 active hydrogen-containing group.