公开(公告)号：EP1903966B1

公开(公告)日：2017-05-17

申请号：EP06764566.3

申请日：2006-07-14

申请人： BIORETEC OY

发明人： TÖRMÄLÄ, Pertti ,  HEINO, Harri ,  VESANEN, Pertti

IPC分类号： B29L31/00 ,  B29C43/00 ,  B29C55/00 ,  A61B17/00

CPC分类号： A61B17/823 ,  A61B2017/00004 ,  B29C43/003 ,  B29C55/00 ,  B29K2995/006 ,  B29L2031/753

公开(公告)号：EP1660146B1

公开(公告)日：2008-12-10

申请号：EP04767137.5

申请日：2004-08-20

申请人： BIORETEC OY

发明人： SUOKAS, Esa ,  TÖRMÄLÄ, Pertti ,  ASHAMMAKHI, Nureddin ,  YLÄNEN, Heimo ,  HUPA, Mikko

IPC分类号： A61F2/28 ,  A61F2/30 ,  A61L27/44 ,  A61L27/56 ,  A61L27/58 ,  B32B5/26 ,  D04B1/14

CPC分类号： B32B5/26 ,  A61F2/28 ,  A61F2/3094 ,  A61F2/30965 ,  A61F2002/2817 ,  A61F2002/30062 ,  A61F2002/30065 ,  A61F2002/30677 ,  A61F2002/30678 ,  A61F2002/30914 ,  A61F2002/30915 ,  A61F2002/30971 ,  A61F2210/0004 ,  A61F2210/0071 ,  A61F2310/00179 ,  A61F2310/00293 ,  A61L27/44 ,  A61L27/56 ,  A61L27/58 ,  B32B2255/02 ,  B32B2255/26 ,  B32B2262/105 ,  B32B2305/08 ,  B32B2556/00 ,  D02G3/448 ,  D04B1/14 ,  D04C1/06 ,  D10B2509/08 ,  Y10T442/2525

摘要： Porous bioabsorbable, bioactive and load-bearing composite medical device structure includes a plurality of regular textile planar layers (1a, lb...) formed of continuous bioabsorbable polymer matrix and bioceramic fibers acting as reinforcements, both included in continuous fibrous elements (3) forming the textile layers. The layers are placed on top of each other to form a structure having two dimensions (x, y) at right angles to each other according to the two dimensions of the textile layer and a third dimension (z) perpendicular to them and resulting from the piling of the layers. A plurality of passages extend through the layers as a result of the openings (2) defined by portions of the continuous fibrous elements (3) extending substantially in the direction of the plane. The continuous fibrous elements (3) comprise both bioactive ceramic reinforcing fibers which form a reinforcing structure and a bioabsorbable polymer matrix material which forms a matrix which binds the layers together and also binds the portions of continuous fibers defining the openings together, thereby forming the passages and stiffening the structure. This bioactive and bioabsorbable composite structure is suitable to be used as a basic structure in medical devices, especially in osteochondral applications where the load-bearing properties of implant are required.

公开(公告)号：EP1660146A1

公开(公告)日：2006-05-31

申请号：EP04767137.5

申请日：2004-08-20

申请人： BIORETEC OY

发明人： SUOKAS, Esa ,  TÖRMÄLÄ, Pertti ,  ASHAMMAKHI, Nureddin ,  YLÄNEN, Heimo ,  HUPA, Mikko

IPC分类号： A61L27/40 ,  A61L31/12 ,  D03D11/00 ,  D04D7/04

CPC分类号： B32B5/26 ,  A61F2/28 ,  A61F2/3094 ,  A61F2/30965 ,  A61F2002/2817 ,  A61F2002/30062 ,  A61F2002/30065 ,  A61F2002/30677 ,  A61F2002/30678 ,  A61F2002/30914 ,  A61F2002/30915 ,  A61F2002/30971 ,  A61F2210/0004 ,  A61F2210/0071 ,  A61F2310/00179 ,  A61F2310/00293 ,  A61L27/44 ,  A61L27/56 ,  A61L27/58 ,  B32B2255/02 ,  B32B2255/26 ,  B32B2262/105 ,  B32B2305/08 ,  B32B2556/00 ,  D02G3/448 ,  D04B1/14 ,  D04C1/06 ,  D10B2509/08 ,  Y10T442/2525

摘要： Porous bioabsorbable, bioactive and load-bearing composite medical device structure includes a plurality of regular textile planar layers (1a, lb...) formed of continuous bioabsorbable polymer matrix and bioceramic fibers acting as reinforcements, both included in continuous fibrous elements (3) forming the textile layers. The layers are placed on top of each other to form a structure having two dimensions (x, y) at right angles to each other according to the two dimensions of the textile layer and a third dimension (z) perpendicular to them and resulting from the piling of the layers. A plurality of passages extend through the layers as a result of the openings (2) defined by portions of the continuous fibrous elements (3) extending substantially in the direction of the plane. The continuous fibrous elements (3) comprise both bioactive ceramic reinforcing fibers which form a reinforcing structure and a bioabsorbable polymer matrix material which forms a matrix which binds the layers together and also binds the portions of continuous fibers defining the openings together, thereby forming the passages and stiffening the structure. This bioactive and bioabsorbable composite structure is suitable to be used as a basic structure in medical devices, especially in osteochondral applications where the load-bearing properties of implant are required.

公开(公告)号：EP1646410B1

公开(公告)日：2009-11-11

申请号：EP04743979.9

申请日：2004-07-19

申请人： BIORETEC OY

发明人： SUOKAS, Esa ,  ASHAMMAKHI, Nureddin ,  TÖRMÄLÄ, Pertti

IPC分类号： A61L17/10 ,  A61F2/02

CPC分类号： A61F2/02 ,  A61F2210/0004 ,  A61F2250/0067 ,  A61L17/005 ,  A61L31/16 ,  A61L2300/00

摘要： The invention relates to synthetic, bioabsorbable polymer materials and implants, like fibres, sutures, meshes and other tissue management, wound closure or tissue engineering devices, which contain: a) a bioabsorbable polymeric matrix; b) antibiotic and/or anti-inflammatory agent particles or mixture thereof, dispersed in the matrix, and c) optionally an additive agent to facilitate device recognition and/or handling to facilitate the use and application of finalized product. In the matrix, cavities around the particles are induced by mechanical processing of the matrix phase. A preferred embodiment of the present invention is a device (suture) that provides a sustained release of antibiotic agent over several days to several weeks for the prevention or treatment of infection. The sutures may be effectively implanted into or in the vicinity of: 1) infected tissue, 2) potentially infected tissue, or in tissues where infection, should it occur, leads to disastrous consequences.

公开(公告)号：EP1631331A1

公开(公告)日：2006-03-08

申请号：EP04739513.2

申请日：2004-06-02

申请人： BIORETEC OY

发明人： TÖRMÄLÄ, Pertti ,  SUOKAS, Esa ,  VEIRANTO, Minna

IPC分类号： A61L24/00 ,  A61L27/44 ,  A61L27/54 ,  A61L27/58 ,  A61L31/12 ,  A61L31/14 ,  A61L31/16 ,  A61K6/083 ,  A61K9/00

CPC分类号： A61K9/0024 ,  A61K9/1647 ,  A61L24/0015 ,  A61L24/0042 ,  A61L24/0089 ,  A61L27/34 ,  A61L27/446 ,  A61L27/46 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L31/127 ,  A61L31/128 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/404 ,  A61L2300/406 ,  A61L2300/45 ,  A61L2300/602 ,  A61L2300/606

摘要： This invention relates to bioabsorbable materials and implants used to prevent and treat infection and promote bone growth. More specifically, this invention relates to synthetic bioabsorbable drug delivery materials and implants comprising: (a) a synthetic bioabsorbable polymeric matrix; (b) an antibiotic phase dispersed into said polymeric matrix; and (c) antibacterial, bioabsorbable, bioactive glass, dispersed into said polymeric matrix for the promotion of bone growth.

公开(公告)号：EP2747799B1

公开(公告)日：2017-06-07

申请号：EP12828168.0

申请日：2012-08-27

申请人： BIORETEC OY

发明人： HEINO, Harri ,  TÖRMÄLÄ, Pertti ,  RÄSÄNEN, Kalle ,  HAARJÄRVI, Jarkko

IPC分类号： A61L31/04 ,  A61B17/58 ,  B29C55/10

CPC分类号： A61B17/8085 ,  A61B17/688 ,  A61B17/7059 ,  A61B17/80 ,  A61B17/8061 ,  A61B2017/00004 ,  A61L31/06 ,  A61L31/128 ,  A61L31/14 ,  A61L31/148 ,  A61L2430/02 ,  B29B11/10 ,  B29C55/10 ,  B29C55/16 ,  B29K2995/0056 ,  B29K2995/006 ,  C08L67/04 ,  A61L31/127

公开(公告)号：EP1874366B1

公开(公告)日：2009-03-18

申请号：EP06725946.5

申请日：2006-04-27

申请人： BIORETEC OY

发明人： TÖRMÄLÄ, Pertti ,  HUTTUNEN, Mikko ,  ASHAMMAKHI, Nureddin ,  TUKIAINEN, Mikko ,  YLÄNEN,Heimo ,  HUPA, Mikko ,  KELLOMÄKI, Minna

IPC分类号： A61L27/40 ,  A61L27/44 ,  A61L27/48

CPC分类号： A61L27/48 ,  A61B2017/00004 ,  A61L27/446 ,  A61L27/58 ,  A61L31/128 ,  A61L31/129 ,  A61L31/148 ,  C08L67/04

摘要： The present invention relates to a bioabsorbable and bioactive composite material for surgical musculoskeletal applications comprising a bioabsorbable polymeric matrix material which is reinforced with bioabsorbable polymeric fibers and bioabsorbable ceramic fibers. The surgical bioabsorbable polymeric matrix material is reinforced with the bioabsorbable polymeric fibers and the bioabsorbable ceramic fibers from which at least a portion is longer than 150 µm. The invention also relates to a method for manufacturing a bioabsorbable and bioactive composite material.

公开(公告)号：EP1903966A1

公开(公告)日：2008-04-02

申请号：EP06764566.3

申请日：2006-07-14

申请人： BIORETEC OY

发明人： TÖRMÄLÄ, Pertti ,  HEINO, Harri ,  VESANEN, Pertti

IPC分类号： A61B17/82

CPC分类号： A61B17/823 ,  A61B2017/00004 ,  B29C43/003 ,  B29C55/00 ,  B29K2995/006 ,  B29L2031/753

摘要： The present invention relates to a bioabsorbable band system for securing a bone fracture, or an osteotomy, or a soft tissue on a bone, the bioabsorbable band system comprising a needle system and a bioabsorbable band (1) including a bioabsorbable locking member (2). The bioabsorbable band (1) comprises a length having an at least partially oriented structure. The bioabsorbable band further comprises a locking mechanism with a locking member (2). The present invention also relates to a method for producing the bioabsorbable band (1).

公开(公告)号：EP1646410A1

公开(公告)日：2006-04-19

申请号：EP04743979.9

申请日：2004-07-19

申请人： BIORETEC OY

发明人： SUOKAS, Esa ,  ASHAMMAKHI, Nureddin ,  TÖRMÄLÄ, Pertti

IPC分类号： A61L17/10 ,  A61F2/02

CPC分类号： A61F2/02 ,  A61F2210/0004 ,  A61F2250/0067 ,  A61L17/005 ,  A61L31/16 ,  A61L2300/00

摘要： The invention relates to synthetic, bioabsorbable polymer materials and implants, like fibres, sutures, meshes and other tissue management, wound closure or tissue engineering devices, which contain: a) a bioabsorbable polymeric matrix; b) antibiotic and/or anti-inflammatory agent particles or mixture thereof, dispersed in the matrix, and c) optionally an additive agent to facilitate device recognition and/or handling to facilitate the use and application of finalized product. In the matrix, cavities around the particles are induced by mechanical processing of the matrix phase. A preferred embodiment of the present invention is a device (suture) that provides a sustained release of antibiotic agent over several days to several weeks for the prevention or treatment of infection. The sutures may be effectively implanted into or in the vicinity of: 1) infected tissue, 2) potentially infected tissue, or in tissues where infection, should it occur, leads to disastrous consequences.

公开(公告)号：EP2747799A1

公开(公告)日：2014-07-02

申请号：EP12828168.0

申请日：2012-08-27

申请人： BIORETEC OY

发明人： HEINO, Harri ,  TÖRMÄLÄ, Pertti ,  RÄSÄNEN, Kalle ,  HAARJÄRVI, Jarkko

IPC分类号： A61L31/04 ,  A61B17/58 ,  B29C55/10

CPC分类号： A61B17/8085 ,  A61B17/688 ,  A61B17/7059 ,  A61B17/80 ,  A61B17/8061 ,  A61B2017/00004 ,  A61L31/06 ,  A61L31/128 ,  A61L31/14 ,  A61L31/148 ,  A61L2430/02 ,  B29B11/10 ,  B29C55/10 ,  B29C55/16 ,  B29K2995/0056 ,  B29K2995/006 ,  C08L67/04 ,  A61L31/127

摘要： A bioabsorbable surgical osteosynthesis plate, operable to be secured by at least one fastener through at least one fastener opening formed in the plate to a bone, comprises a flat section having first and second surfaces defining a main plane (the sheet plane) of the plate. The plate is formed from a polymer material (including polymer, copolymer and/or polymer alloys) that is oriented multiaxially and is substantially rigid and substantially deformable at a first thermochemical state. In the multiaxially oriented structure of the plate the polymer material is arranged according to three or more different orientation axes along the main plane of the plate as a result of solid state drawing of the plate. The polymer material of the plate has isotropic mechanical tear properties in different directions along the main plane of the plate.