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公开(公告)号：EP1461325A1
公开(公告)日：2004-09-29
申请号：EP02789090.4
申请日：2002-11-22
申请人： BIOVITRUM AB
发明人： BARF, Tjeerd , EMOND, Rikard , KURZ, Guido , VALLG RDA, Jerk , NILSSON, Marianne , ZHANG, Lian
IPC分类号： C07D277/52
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D277/52 , C07D417/06 , C07D417/12 , C07D417/14
摘要： The present invention relates to compounds with the formula (I), and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament which acts on the human 11-b-hydroxysteroid dehydrogenase type 1 enzyme.
摘要翻译： 本发明涉及具有式（I）的化合物，还涉及包含该化合物的药物组合物，以及该化合物在药物中的用途以及用于制备作用于人类11-β-羟基类固醇的药物的用途 脱氢酶1型酶。
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公开(公告)号：EP1283833A1
公开(公告)日：2003-02-19
申请号：EP01938885.9
申请日：2001-05-22
申请人： BIOVITRUM AB
发明人： BARF, Tjeerd , NILSSON, Marianne , KURZ, Guido , VALLGARDA, Jerk
IPC分类号： C07D277/52 , A61K31/426 , A61P3/00 , A61P5/48 , A61P27/06 , A61P25/24 , A61P25/28 , A61P29/00 , A61P31/12 , A61P31/06
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D277/52 , C07D277/56 , C07D277/84 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14 , C07D491/08 , C07D513/04
摘要： The present invention relates to compounds with the formula (I) and also to pharmaceutical compositions comprising the compounds, to processes for their preparation, as well as to the use of the compounds in medicine and for the preparation of a medicament which acts on the human 11-β-hydroxysteroid dehydrogenase type 1 enzyme.
摘要翻译： 本发明涉及具有式（I）的化合物以及包含该化合物的药物组合物，其制备方法，以及该化合物在药物中的用途以及制备作用于人的药物的用途 11-β-羟基类固醇脱氢酶1型酶。
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公开(公告)号：EP1283832B1
公开(公告)日：2010-10-20
申请号：EP01934782.2
申请日：2001-05-22
申请人： BIOVITRUM AB
发明人： KURZ, Guido , NILSSON, Marianne
IPC分类号： C07D277/52 , C07D277/60 , A61K31/426 , A61P3/00 , A61P5/48 , A61P27/06 , A61P25/24 , A61P25/28 , A61P29/00 , A61P31/12 , A61P31/06
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D277/52 , C07D277/56 , C07D277/84 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14 , C07D491/08 , C07D513/04
摘要： The present invention relates to compounds with the formula (I) and also to pharmaceutical compositions comprising the compounds, to processes for their preparation, as well as to the use of the compounds in medicine and for the preparation of a medicament which acts on the human 11-β-hydroxysteroid dehydrogenase type 1 enzyme.
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公开(公告)号：EP1461325B1
公开(公告)日：2010-05-26
申请号：EP02789090.4
申请日：2002-11-22
申请人： BIOVITRUM AB
发明人： BARF, Tjeerd , EMOND, Rikard , KURZ, Guido , VALLGÅRDA, Jerk , NILSSON, Marianne , ZHANG, Lian
IPC分类号： C07D277/52
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D277/52 , C07D417/06 , C07D417/12 , C07D417/14
摘要： The present invention relates to compounds with the formula (I), and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament which acts on the human 11-b-hydroxysteroid dehydrogenase type 1 enzyme.
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公开(公告)号：EP1461333A1
公开(公告)日：2004-09-29
申请号：EP02789088.8
申请日：2002-11-22
申请人： BIOVITRUM AB
IPC分类号： C07D333/36 , A61K31/381 , A61P3/00 , A61P9/12 , A61P19/10 , A61P25/00 , A61P27/06 , A61P29/00
CPC分类号： C07D409/12 , A61K31/381 , A61K31/433 , C07D333/36 , C07D409/14
摘要： The present invention relates to compounds with the formula (I)and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament which acts on the human 11-b-hydroxysteroid dehydrogenase type 1 enzyme.
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公开(公告)号：EP1461327A1
公开(公告)日：2004-09-29
申请号：EP02789089.6
申请日：2002-11-22
申请人： BIOVITRUM AB
IPC分类号： C07D285/08 , C07D285/135 , A61K31/433 , A61P3/00 , A61P9/12 , A61P19/10 , A61P25/00 , A61P27/06 , A61P29/00 , A61P31/00
CPC分类号： C07D285/08 , A61K31/381 , A61K31/433 , C07D231/12 , C07D233/56 , C07D249/08 , C07D285/135 , C07D333/36 , C07D409/14 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14
摘要： The present invention relates to compounds with the formula (I), and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament which acts on the human 11-b-hydroxysteroid dehydrogenase type 1 enzyme.
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公开(公告)号：EP1283832A1
公开(公告)日：2003-02-19
申请号：EP01934782.2
申请日：2001-05-22
申请人： BIOVITRUM AB
发明人： KURZ, Guido , NILSSON, Marianne
IPC分类号： C07D277/52 , C07D277/60 , A61K31/426 , A61P3/00 , A61P5/48 , A61P27/06 , A61P25/24 , A61P25/28 , A61P29/00 , A61P31/12 , A61P31/06
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D277/52 , C07D277/56 , C07D277/84 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14 , C07D491/08 , C07D513/04
摘要： The present invention relates to compounds with the formula (I) and also to pharmaceutical compositions comprising the compounds, to processes for their preparation, as well as to the use of the compounds in medicine and for the preparation of a medicament which acts on the human 11-β-hydroxysteroid dehydrogenase type 1 enzyme.
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公开(公告)号：EP1283831A1
公开(公告)日：2003-02-19
申请号：EP01934781.4
申请日：2001-05-22
申请人： BIOVITRUM AB
发明人： BARF, Tjeerd , EMOND, Rikard , KURZ, Guido , VALLG RDA, Jerk , NILSSON, Marianne
IPC分类号： C07D277/52 , A61K31/426 , A61P3/00 , A61P5/48 , A61P27/06 , A61P25/24 , A61P25/28 , A61P29/00 , A61P31/12 , A61P31/06
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D277/52 , C07D277/56 , C07D277/84 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14 , C07D491/08 , C07D513/04
摘要： The present invention relates to compounds with the formula (II) and also to pharmaceutical compositions comprising the compounds, to processes for their preparation, as well as to the use of thecompounds in medicine and for the preparation of a medicament which acts on the human 11-β-hydroxysteroid dehydrogenase type 1 enzyme.
摘要翻译： 本发明涉及具有式（II）的化合物，还涉及包含所述化合物的药物组合物，其制备方法，以及该化合物在药物中的用途以及用于制备作用于人11的药物的用途 -β-羟基类固醇脱氢酶1型酶。
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