公开(公告)号：EP2449386A4

公开(公告)日：2013-11-13

申请号：EP10794415

申请日：2010-06-29

申请人： BOVIN NIKOLAI VLADIMIROVICH ,  HENRY STEPHEN MICHEAL ,  PARKER STEPHEN ROBERT

发明人： BOVIN NIKOLAI VLADIMIROVICH ,  HENRY STEPHEN MICHEAL ,  PARKER STEPHEN ROBERT

IPC分类号： G01N33/80

CPC分类号： G01N33/5308 ,  G01N33/92

摘要： Methods of manufacturing cards, strips and multiwell plates for use in diagnostic assays are described. The methods employ the use of synthetic constructs of the generic structure F-S-L (where F is an antigen for a reactive antibody, S is a spacer covalently linking F to L, and L is a lipid) as “ink” in inkjet printers. The cards, strips and multiwell plates provide a number of advantages including efficiency of manufacture and improved accuracy in determining and recording assay results.

公开(公告)号：EP2795316A4

公开(公告)日：2015-07-01

申请号：EP12880480

申请日：2012-12-19

申请人： HENRY STEPHEN MICHEAL ,  PARKER STEPHEN ROBERT

发明人： HENRY STEPHEN MICHEAL ,  PARKER STEPHEN ROBERT

IPC分类号： G01N33/48 ,  G01N33/53 ,  G01N33/543

CPC分类号： G01N1/4077 ,  B01D65/08 ,  C08G64/42 ,  C12Q1/02 ,  C12Q1/24 ,  G01N33/54353 ,  G01N33/54393 ,  G01N2001/4088

摘要： Biocompatible methods of functionalising inert surfaces for use in biological applications are described. The methods employ the use of synthetic constructs of the generic structure F-S-L (where F is a functional moiety, S is a spacer selected to provide a construct that is dispersible in water, and L is a diacyl- or dialkyl-glycerophospholipid). An object of the invention is to localise or immobilise functional moieties to the inert surface of a substrate wherein the surface is comprised of glass, silver, polyamide, polycarbonate, polypropylene, polyethersulfone, polytetrafluoroethylene or polyvinylidene fluoride, and the substrate is comprised of a fibre, membrane, microsphere or nanosphere.

摘要翻译： 描述了用于生物应用的功能化惰性表面的生物相容性方法。 该方法采用通用结构F-S-L的合成构建体（其中F是功能部分，S是选择用于提供可分散在水中的构建体，L是二酰基或二烷基 - 甘油磷脂）的间隔物。 本发明的目的是将功能部分定位或固定在基材的惰性表面上，其中表面由玻璃，银，聚酰胺，聚碳酸酯，聚丙烯，聚醚砜，聚四氟乙烯或聚偏二氟乙烯组成，基材由纤维 ，膜，微球或纳米球。