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公开(公告)号:EP2408466A4
公开(公告)日:2013-08-28
申请号:EP10754107
申请日:2010-03-18
发明人: DUFFIELD JEREMY , LANG RICHARD A
IPC分类号: A61K38/16 , A61K39/395 , A61P1/00 , A61P9/00 , A61P21/00
CPC分类号: A61K38/16 , G01N33/6872 , G01N33/6893
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公开(公告)号:EP2914279A4
公开(公告)日:2016-07-06
申请号:EP13851855
申请日:2013-11-01
发明人: DUFFIELD JEREMY , REN SHUYU , HEGDE RASHMI
IPC分类号: A61K38/17
CPC分类号: C07K14/4703 , A61K38/1709
摘要: The present disclosure provides molecules, compositions and methods for treating scarring in organs. The molecules, compositions and methods treat scarring by modulating the WNT, platelet-derived growth factor receptor (PDGFR), transforming growth factor-beta (TGF3) and/or connective-tissue growth factor (CTGF) signaling pathways.
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