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公开(公告)号：EP1003501B1
公开(公告)日：2005-03-09
申请号：EP98917992.4
申请日：1998-04-02
IPC分类号： A61K31/195 , A61K31/57 , A61K31/58 , A61K31/405 , A61K31/135 , A61K31/60
CPC分类号： A61K31/135 , A61K31/195 , A61K31/35 , A61K31/385 , A61K31/40 , A61K31/405 , A61K31/57 , A61K31/58 , A61K31/60 , A61K49/0004 , G01N33/6893 , G01N2800/32 , G01N2800/323 , G01N2800/324 , Y10S436/811
摘要： The invention involves methods for characterizing an individual's risk profile of developing a future cardiovascular disorder by obtaining a level of the marker of systemic inflammation in the individual. The invention also involves methods for evaluating the likelihood that an individual will benefit from treatment with an agent for reducing the risk of future cardiovascular disorder.
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公开(公告)号：EP1003501B9
公开(公告)日：2005-06-08
申请号：EP98917992.4
申请日：1998-04-02
IPC分类号： A61K31/195 , A61K31/57 , A61K31/58 , A61K31/405 , A61K31/135 , A61K31/60
CPC分类号： A61K31/135 , A61K31/195 , A61K31/35 , A61K31/385 , A61K31/40 , A61K31/405 , A61K31/57 , A61K31/58 , A61K31/60 , A61K49/0004 , G01N33/6893 , G01N2800/32 , G01N2800/323 , G01N2800/324 , Y10S436/811
摘要： The invention involves methods for characterizing an individual's risk profile of developing a future cardiovascular disorder by obtaining a level of the marker of systemic inflammation in the individual. The invention also involves methods for evaluating the likelihood that an individual will benefit from treatment with an agent for reducing the risk of future cardiovascular disorder.
摘要翻译： 本发明涉及通过获得个体中全身炎症标志物水平来表征个体发展未来心血管疾病的风险特征的方法。 本发明还涉及评估个体将受益于用于降低未来心血管疾病风险的药剂治疗的可能性的方法。
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3.发明公开SYSTEMIC INFLAMMATORY MARKERS AS DIAGNOSTIC TOOLS IN THE PREVENTION OF ATHEROSCLEROTIC DISEASES 审中-公开系统性炎症标志物作为诊断工具，动脉粥样硬化疾病预防
公开(公告)号：EP1212101A1
公开(公告)日：2002-06-12
申请号：EP00959851.7
申请日：2000-08-31
CPC分类号： A61K45/06 , A61K31/00 , A61K31/616 , G01N2333/4737 , G01N2333/52 , G01N2333/70525 , G01N2800/2871 , A61K2300/00
摘要： The invention involves methods for characterizing an individual's risk profile of developing a future cardiovascular disorder by obtaining a level of the marker of systemic inflammation in the individual. The invention also involves methods for evaluating the likelihood that an individual will benefit from treatment with an agent for reducing the risk of future cardiovascular disorder.
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4.发明公开MEANS OF ASCERTAINING AN INDIVIDUAL'S RISK PROFILE FOR ATHEROSCLEROTIC DISEASE 无效A的使用的方式来降低心血管疾病的风险
公开(公告)号：EP1003501A1
公开(公告)日：2000-05-31
申请号：EP98917992.4
申请日：1998-04-02
IPC分类号： A61K31/195 , A61K31/57 , A61K31/58 , A61K31/405 , A61K31/135 , A61K31/60
CPC分类号： A61K31/135 , A61K31/195 , A61K31/35 , A61K31/385 , A61K31/40 , A61K31/405 , A61K31/57 , A61K31/58 , A61K31/60 , A61K49/0004 , G01N33/6893 , G01N2800/32 , G01N2800/323 , G01N2800/324 , Y10S436/811
摘要： The invention involves methods for characterizing an individual's risk profile of developing a future cardiovascular disorder by obtaining a level of the marker of systemic inflammation in the individual. The invention also involves methods for evaluating the likelihood that an individual will benefit from treatment with an agent for reducing the risk of future cardiovascular disorder.
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5.发明公开BETA-CAROTENE AND VITAMIN E THERAPY FOR INHIBITION OF MAJOR VASCULAR EVENTS 失效治疗基于β-胡萝卜素和维生素E以大代抑制血管事件。
公开(公告)号：EP0551427A1
公开(公告)日：1993-07-21
申请号：EP91919463.0
申请日：1991-09-27
CPC分类号： A61K31/355 , A61K31/015 , A61K31/07 , A61K31/60 , Y10S514/824 , A61K2300/00
摘要： L'invention se rapporte à un procédé qui permet de prévenir les accidents vasculaires majeurs chez un sujet auquel on administre de la bêta-carotène et/ou de la vitamine E, soit seules soit combinées. On administre la bêta-carotène et/ou la vitamine E de façon à réduire le risque qu'a le sujet de subir un accident vasculaire majeur. Dans un autre mode de réalisation préféré, on obtient un effet particulièrement efficace en combinant la bêta-carotène avec de l'aspirine. L'invention se rapporte en outre à des compositions pharmaceutiques contenant de la bêta-carotène combinée à de la vitamine E.
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