公开(公告)号：EP0674497B1

公开(公告)日：2002-07-24

申请号：EP94902302.2

申请日：1993-11-16

申请人： BROWN UNIVERSITY RESEARCH FOUNDATION

发明人： GENTILE, Frank, T. ,  TRESCO, Patrick, A. ,  HAZLETT, Tyrone ,  FLANAGAN, Thomas ,  DOHERTY, Edward, J. ,  REIN, David ,  HOLLAND, Laura

IPC分类号： A61F13/00 ,  A61K9/48 ,  A61K9/00

CPC分类号： A61K9/0024

摘要： Microporous macrocapsules are disclosed which are useful as implantation devices for cell therapy. The macrocapsule comprises living cells that secrete biological substance that are therapeutically useful and that are released from the macrocapsule to the site of implantation. The capsules can have selected permeability characteristics based upon their particular usage and desired viral retentivity characteristics.

公开(公告)号：EP0674497A1

公开(公告)日：1995-10-04

申请号：EP94902302.0

申请日：1993-11-16

申请人： BROWN UNIVERSITY RESEARCH FOUNDATION

发明人： GENTILE, Frank, T. ,  TRESCO, Patrick, A. ,  HAZLETT, Tyrone ,  FLANAGAN, Thomas ,  DOHERTY, Edward, J. ,  REIN, David ,  HOLLAND, Laura

IPC分类号： C12Q1 ,  A61K9 ,  A61K35 ,  C12N5 ,  C12N7

CPC分类号： A61K9/0024

摘要： Microporous macrocapsules are disclosed which are useful as implantation devices for cell therapy. The macrocapsule comprises living cells that secrete biological substance that are therapeutically useful and that are released from the macrocapsule to the site of implantation. The capsules can have selected permeability characteristics based upon their particular usage and desired viral retentivity characteristics.