公开(公告)号：EP1895008A3

公开(公告)日：2009-11-11

申请号：EP07014821.8

申请日：2000-08-03

申请人： Bacher, Adelbert ,  Zenk, Meinhart H.

发明人： Bacher, Adelbert ,  Zenk, Meinhart H. ,  Eisenreich, Wolfgang ,  Fellermeier, Monika ,  Fischer, Markus ,  Hecht, Stefan ,  Herz, Stefan ,  Kis, Klaus ,  Lüttgen, Holger ,  Rohdich, Felix ,  Sagner, Silvia ,  Schuhr, Christoph A. ,  Wungsintaweekul, Juraithip c/o Dep.of Pharmacognosy and Pharmaceutical Botany

IPC分类号： C12N15/54 ,  C12N15/60 ,  C12N9/12 ,  C12N9/88 ,  G01N33/68 ,  A01N61/00 ,  C12P23/00

CPC分类号： C12N9/1229 ,  C12N9/1205 ,  C12N9/88 ,  C12P23/00

摘要： The present invention relates to enzymatic activity involved in isoprenoid biosynthesis as well as to inhibitors, notably herbicides, for enzymes in the biosynthesis of isoprenoids. More specifically, the present invention relates to screening methods for detecting such inhibitors, and to enzymatically active proteins for performing said methods as well as purified-isolated DNA coding for such proteins. Moreover, the present invention relates to novel inhibitors detectable by said screening methods as well as compositions and processes for inhibiting the synthesis of isoprenoids and for controlling the growth of organisms based on said inhibitors. The invention relates also to the development of inhibitor-resistant plant enzymes and plants, plant tissues, plant seeds and plant cells.

公开(公告)号：EP1895008A2

公开(公告)日：2008-03-05

申请号：EP07014821.8

申请日：2000-08-03

申请人： Bacher, Adelbert ,  Zenk, Meinhart H.

发明人： Bacher, Adelbert ,  Zenk, Meinhart H. ,  Eisenreich, Wolfgang ,  Fellermeier, Monika ,  Fischer, Markus ,  Hecht, Stefan ,  Herz, Stefan ,  Kis, Klaus ,  Lüttgen, Holger ,  Rohdich, Felix ,  Sagner, Silvia ,  Schuhr, Chrisoph A. ,  Wungsintaweekul, Juraithip c/o Dep.of Pharmacognosy and Pharmaceutical Botany

IPC分类号： C12N15/54 ,  C12N15/60 ,  C12N9/12 ,  C12N9/88 ,  C12P23/00

CPC分类号： C12N9/1229 ,  C12N9/1205 ,  C12N9/88 ,  C12P23/00

摘要： The present invention relates to enzymatic activity involved in isoprenoid biosynthesis as well as to inhibitors, notably herbicides, for enzymes in the biosynthesis of isoprenoids. More specifically, the present invention relates to screening methods for detecting such inhibitors, and to enzymatically active proteins for performing said methods as well as purified-isolated DNA coding for such proteins. Moreover, the present invention relates to novel inhibitors detectable by said screening methods as well as compositions and processes for inhibiting the synthesis of isoprenoids and for controlling the growth of organisms based on said inhibitors. The invention relates also to the development of inhibitor-resistant plant enzymes and plants, plant tissues, plant seeds and plant cells.

摘要翻译： 本发明涉及涉及类异戊二烯生物合成的酶活性以及用于类异戊二烯生物合成中的酶的抑制剂，特别是除草剂。 更具体地，本发明涉及用于检测这些抑制剂的筛选方法，以及用于进行所述方法的酶活性蛋白质以及编码这种蛋白质的纯化分离的DNA。 此外，本发明涉及可通过所述筛选方法检测的新型抑制剂以及基于所述抑制剂抑制类异戊二烯的合成和控制生物的组合物和方法。 本发明还涉及抑制剂抗性植物酶和植物，植物组织，植物种子和植物细胞的发展。