公开(公告)号：EP2326285B1

公开(公告)日：2012-02-15

申请号：EP09751282.6

申请日：2009-05-18

申请人： Bausch & Lomb Incorporated ,  Rochester Institute of Technology ,  University Of Rochester

发明人： SMITH, Thomas ,  KNOX, Wayne, H. ,  DING, Li ,  JANI, Dharmendra, M. ,  LINHARDT, Jeffrey, G.

IPC分类号： A61F2/16

CPC分类号： A61F9/00804 ,  A61F2/1451 ,  A61F2/1627 ,  A61F2/1635 ,  A61L27/50 ,  A61L27/52 ,  A61L2430/16 ,  B29D11/00009 ,  G02C2202/14

摘要： An intraocular lens comprising an optical, polymeric material with predetermine regions that have been irradiated with light from a laser to form refractive structures. The refractive structures are characterized by a change in refractive index within the irradiated regions of the lens with little or no scattering loss. To facilitate the formation of the refractive structures the optical, polymeric material is prepared from at least one monomer having a photofunctional group, the monomer having a two-photon cross- section of at least 10 GM. The invention is also directed to a method for modifying the refractive index of an intraocular lens prior to the surgical insertion of the lens in a human eye. The described irradiation process is used in a manufacturing environment to create refractive structures in the intraocular lens. The method includes irradiating a solvated intraocular lens at predetermined regions with light from a laser to form refractive structures.

公开(公告)号：EP2713950A1

公开(公告)日：2014-04-09

申请号：EP12724845.8

申请日：2012-05-29

申请人： Bausch & Lomb Incorporated ,  University of Rochester

发明人： SMITH, Thomas ,  KNOX, Wayne, H. ,  JANI, Dharmendra, M. ,  DING, Li

IPC分类号： A61F2/16 ,  A61F9/008 ,  A61L27/52

CPC分类号： G02B3/0087 ,  A61F2/1618 ,  A61F2/1627 ,  A61F9/00834 ,  A61L27/16 ,  A61L27/50 ,  A61L27/52 ,  A61L2400/18 ,  A61L2430/16 ,  G02B2003/0093 ,  G02C2202/12 ,  G02C2202/14 ,  C08L33/10

摘要： A method for modifying the refractive index of an optical polymeric material. The method comprises continuously irradiating predetermined regions of an optical, polymeric material with femtosecond laser pulses to form a gradient index refractive structure within the material. An optical device includes an optical, polymeric lens material having an anterior surface and posterior surface and an optical axis intersecting the surfaces and at least one laser-modified, GRIN layer disposed between the anterior surface and the posterior surface and arranged along a first axis 45° to 90° to the optical axis, and further characterized by a variation in index of refraction across at least one of at least a portion of the adjacent segments and along each segment.

公开(公告)号：EP2326285A2

公开(公告)日：2011-06-01

申请号：EP09751282.6

申请日：2009-05-18

申请人： Bausch & Lomb Incorporated ,  Rochester Institute of Technology ,  University Of Rochester

发明人： SMITH, Thomas ,  KNOX, Wayne, H. ,  DING, Li ,  JANI, Dharmendra, M. ,  LINHARDT, Jrffrey, G.

IPC分类号： A61F2/16

CPC分类号： A61F9/00804 ,  A61F2/1451 ,  A61F2/1627 ,  A61F2/1635 ,  A61L27/50 ,  A61L27/52 ,  A61L2430/16 ,  B29D11/00009 ,  G02C2202/14

摘要： An intraocular lens comprising an optical, polymeric material with predetermine regions that have been irradiated with light from a laser to form refractive structures. The refractive structures are characterized by a change in refractive index within the irradiated regions of the lens with little or no scattering loss. To facilitate the formation of the refractive structures the optical, polymeric material is prepared from at least one monomer having a photofunctional group, the monomer having a two-photon cross- section of at least 10 GM. The invention is also directed to a method for modifying the refractive index of an intraocular lens prior to the surgical insertion of the lens in a human eye. The described irradiation process is used in a manufacturing environment to create refractive structures in the intraocular lens. The method includes irradiating a solvated intraocular lens at predetermined regions with light from a laser to form refractive structures.