利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

5 条记录 (耗时 0.012 秒)

    VIRUS FILTRATION OF CELL CULTURE MEDIA
    1.
    发明公开
    VIRUS FILTRATION OF CELL CULTURE MEDIA 审中-公开
    病毒培养基的病毒过滤

    公开(公告)号：EP3103861A1

    公开(公告)日：2016-12-14

    申请号：EP16181886.9

    申请日：2013-06-13

    申请人： Baxalta GmbH ,  Baxalta Incorporated

    发明人： MUNDT, Wolfgang ,  MITTERER, Artur ,  REITER, Manfred ,  HASSLACHER, Meinhard ,  GRILLBERGER, Leopold ,  KREIL, Thomas

    IPC分类号： C12M1/00 ,  A61L2/00 ,  C12M1/12 ,  C12N5/00

    摘要： The invention relates to a method for removing a viral contaminant from a preparation, being a cell culture medium or at least a component of a cell culture medium. The method comprises subjecting said preparation to filtration for at least about 24 hours through a virus filter having an effective pore size of maximum about 75 nm. Further, the invention relates to the use of a virus filter in filtration of at least about 24 hours, wherein the virus filter has an effective pore size of maximum about 75 nm for the removal of viral contaminant from a preparation, being a cell culture medium or at least a component of a cell culture medium. In some embodiments the filtration according to the invention operates at a volumetric capacity of at least about 2000 L/m 2 . Further, the invention relates to the use of a preparation, being a cell culture medium or at least a component of a cell culture medium obtainable according to method of the invention for cell culture; pharmaceutical, diagnostic and/or cosmetic preparations as well as in food preparations.

    摘要翻译： 本发明涉及从制剂中除去病毒污染物的方法，所述制剂是细胞培养基或细胞培养基的至少一种组分。 该方法包括使所述制剂经过具有最大约75nm有效孔径的病毒过滤器过滤至少约24小时。 此外，本发明涉及病毒过滤器在过滤中至少约24小时的用途，其中病毒过滤器具有最大约75nm的有效孔径，用于从制剂中去除病毒污染物，所述制剂是细胞培养基 或细胞培养基的至少一种组分。 在一些实施方案中，根据本发明的过滤在至少约2000L / m 2的体积容量下操作。 此外，本发明涉及作为细胞培养基或可根据本发明的方法获得的细胞培养基的至少一种组分用于细胞培养的制剂的用途; 制药，诊断和/或化妆品制剂以及食品制剂。