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    COMPOSITIONS COMPRISING RECOMBINANT BACILLUS CELLS AND ANOTHER BIOLOGICAL CONTROL AGENT
    2.
    发明公开
    COMPOSITIONS COMPRISING RECOMBINANT BACILLUS CELLS AND ANOTHER BIOLOGICAL CONTROL AGENT 审中-公开
    包含重组BACILLUS细胞和另一种生物控制剂的组合物

    公开(公告)号：EP3193619A1

    公开(公告)日：2017-07-26

    申请号：EP15772140.8

    申请日：2015-09-17

    申请人： Bayer CropScience LP ,  Spogen Biotech Inc.

    发明人： CURTIS, Damian ,  THOMPSON, Brian

    IPC分类号： A01N63/00 ,  A01N63/04 ,  A01P21/00

    CPC分类号： C07K14/325 ,  A01N25/00 ,  A01N63/00 ,  A61K38/00 ,  C12N15/00 ,  C12N15/63 ,  C12N15/82 ,  C12N15/866 ,  A01N63/04

    摘要： The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one further biological control agent selected from particular microorganisms disclosed herein and/or a mutant of a specific strain of a microorganism disclosed herein having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.

    摘要翻译： 本发明涉及一种组合物，其包含：a）表达融合蛋白的产生重组芽孢杆菌细胞，所述融合蛋白包含：（i）至少一种植物生长刺激蛋白或肽和（ii）将融合蛋白定位于外生孢子 的芽孢杆菌细胞; 和b）选自本文公开的特定微生物的至少一种其他生物防治剂和/或本文公开的微生物特定菌株的突变体，其具有各自菌株的全部鉴定特征，和/或由各自产生的至少一种代谢产物 和/或由相应菌株产生的至少一种代谢物，其以协同有效量表现出对昆虫，螨，线虫和/或植物病原体的活性。 此外，本发明涉及该组合物的用途以及增强植物生长，促进植物健康，和/或减少植物和植物部分的总体损害的方法。

    COMPOSITIONS COMPRISING RECOMBINANT BACILLUS CELLS AND A FUNGICIDE
    6.
    发明公开
    COMPOSITIONS COMPRISING RECOMBINANT BACILLUS CELLS AND A FUNGICIDE 审中-公开
    包含重组芽孢杆菌细胞和杀真菌剂的组合物

    公开(公告)号：EP3203842A1

    公开(公告)日：2017-08-16

    申请号：EP15771419.7

    申请日：2015-09-17

    申请人： Bayer CropScience LP

    发明人： CURTIS, Damian ,  THOMPSON, Brian

    IPC分类号： A01N63/00 ,  A01N43/30 ,  A01N43/54 ,  A01N55/04 ,  A01N43/80 ,  A01N47/32 ,  A01N43/50 ,  A01N37/50

    CPC分类号： A01N63/00 ,  A01N37/50 ,  A01N43/80 ,  C12Y302/01004 ,  C12Y302/01132

    摘要： The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one particular fungicide disclosed herein in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.

    摘要翻译： 本发明涉及一种组合物，其包含：a）表达融合蛋白的产生重组芽孢杆菌细胞，所述融合蛋白包含：（i）至少一种植物生长刺激蛋白或肽和（ii）将融合蛋白定位于外生孢子 的芽孢杆菌细胞; 和b）协同有效量的至少一种本文公开的特定杀真菌剂。 此外，本发明涉及该组合物的用途以及增强植物生长，促进植物健康，和/或减少植物和植物部分的总体损害的方法。

    PROCESS FOR PRODUCING GOUGEROTIN EMPLOYING STREPTOMYCES MICROFLAVUS STRAINS
    7.
    发明公开
    PROCESS FOR PRODUCING GOUGEROTIN EMPLOYING STREPTOMYCES MICROFLAVUS STRAINS 审中-公开
    使用链霉菌产生鼠曲霉的方法微螺旋菌菌株

    公开(公告)号：EP2906710A2

    公开(公告)日：2015-08-19

    申请号：EP13785692.8

    申请日：2013-10-11

    申请人： Bayer CropScience LP

    发明人： CAMPBELL, Brian ,  CURTIS, Damian ,  GUAN, Shaohua ,  GUILHABERT-GOYA, Magalie ,  JOO, Daniel, M. ,  LU, Tara ,  MARGOLIS, Jonathan, S. ,  ROYALTY, Reed, Nathan ,  SALAZAR, Gerardo, Bueno ,  SESIN, David ,  SMITH, Frisby, Davis ,  TAYLOR, Colleen ,  ZHU, Hong

    IPC分类号： C12P19/38 ,  C07H19/06 ,  A01N43/54 ,  A01N63/02

    CPC分类号： A01N63/02 ,  A01N43/54 ,  C12P19/28 ,  C12P19/385

    摘要： The present invention relates to novel strains of Streptomyces microflavus and methods of their use for controlling diseases or pests of a plant. The invention also relates to a fermentation broth obtained by cultivating a gougerotin producing Streptomyces strain, wherein the fermentation broth contains at least about 1 g/L gougerotin. The invention also relates to a method of producing a fermentation broth of a gougerotin producing Streptomyces strain, wherein the fermentation broth contains at least about 1 g/L gougerotin, the method comprising cultivating the Streptomyces strain in a culture medium containing a digestible carbon source and a digestible nitrogen source under aerobic conditions, wherein the culture medium contains an amino acid at a concentration effective to achieve a gougerotin concentration of at least 1 g/L. The present disclosure also relates to the molecular cloning of a gougerotin biosynthetic gene cluster from Streptomyces microflavus, and identification of individual genes in the gene cluster as well as the proteins encoded thereby. A gougerotin gene cluster comprising 13 open reading frames (ORFs) is located within a genetic locus of Streptomyces microflavus.

    摘要翻译： 本发明涉及新的微小链霉菌菌株及其用于防治植物病害或害虫的方法。 本发明还涉及通过培养产生毛霉素的链霉菌菌株获得的发酵液，其中发酵液含有至少约1g / L的毛色素。 本发明还涉及制备产生古口红素链霉菌菌株的发酵液的方法，其中所述发酵液含有至少约1g / L古毛青素，所述方法包括在含有可消化碳源的培养基中培养链霉菌菌株和 在有氧条件下的可消化的氮源，其中所述培养基含有有效实现至少1g / L的古河豚菌素浓度的浓度的氨基酸。 本发明还涉及来自链霉菌微链霉菌的古格曲菌生物合成基因簇的分子克隆，以及基因簇中单个基因的鉴定以及由此编码的蛋白质。 包含13个开放阅读框架（ORF）的牙渍素基因簇位于微链霉菌的遗传基因座内。