公开(公告)号：EP1357932B1

公开(公告)日：2004-12-15

申请号：EP02716073.8

申请日：2002-01-21

申请人： Bayer HealthCare AG

发明人： KALBE, Jochen ,  TRAEUBEL, Michael ,  HARDER, Achim ,  VON SAMSON-HIMMELSTJERNA, Georg

IPC分类号： A61K38/15 ,  A61P33/00

CPC分类号： A61K38/15

摘要： The invention relates to the use of crystal modification (I) of a cyclic depsipeptide of formula (I) for producing medicaments, particularly for combating endoparasites.

公开(公告)号：EP1301188B1

公开(公告)日：2004-10-13

申请号：EP01957894.7

申请日：2001-06-26

申请人： Bayer HealthCare AG

发明人： HARDER, Achim ,  VON SAMSON-HIMMELSTJERNA, Georg ,  KRÜGER, Bernd-Wieland ,  MEHLHORN, Heinz ,  SCHMIDT, Jürgen

IPC分类号： A61K31/5375 ,  A01N43/84 ,  A01N47/38

CPC分类号： A61K31/5375

摘要： The invention relates to agents that contain certain active substances that are useful as repellents, and to their use for preventing humans or animals from being infected with the infective stages of parasitic flatworms (platyhelminths).

公开(公告)号：EP1296655B1

公开(公告)日：2008-07-16

申请号：EP01957856.6

申请日：2001-06-18

申请人： Bayer HealthCare AG

发明人： KALBE, Jochen ,  GEISSLER, Kornelia ,  TRÄUBEL, Michael ,  HARDER, Achim ,  VON SAMSON-HIMMELSTJERNA, Georg

IPC分类号： A61K9/20

CPC分类号： A61K9/0056

摘要： The invention relates to orally administered medicaments for animals, which are voluntarily ingested by the latter (e.g. dogs, cats and horses). The invention also relates to a method for producing said agents and to the use thereof, in particular as endoparasiticides.

公开(公告)号：EP1189615B1

公开(公告)日：2004-02-04

申请号：EP00940235.5

申请日：2000-05-04

申请人： Bayer HealthCare AG

发明人： HARDER, Achim ,  VON SAMSON-HIMMELSTJERNA, Georg

IPC分类号： A61K31/495 ,  A61K38/15 ,  A61P33/00

CPC分类号： A61K31/495 ,  A61K38/15 ,  A61K2300/00

摘要： The invention relates to the use of piperazines for potentiating the endoparasiticidal action of cyclic depsipeptides in endoparasiticidal agents. Said depsipeptides are comprised of amino acids and hydroxycarboxylic acids serving as ring structural elements and having 24 ring atoms. The invention also relates to agents of this type and to the use of piperazines and cyclic depsipeptides, said depsipeptides being comprised of amino acids and hydroxycarboxylic acids serving as ring structural elements and having 24 ring atoms, in order to produce endoparasiticidal agents.

公开(公告)号：EP1259250B1

公开(公告)日：2006-10-25

申请号：EP01911623.5

申请日：2001-02-09

申请人： Bayer HealthCare AG

发明人： KALBE, Jochen ,  TRÄUBEL, Michael ,  VON SAMSON-HIMMELSTJERNA, Georg ,  HARDER, Achim ,  STEGEMANN, Michael ,  MENCKE, Norbert

IPC分类号： A61K38/15 ,  A61K47/22 ,  A61K47/10 ,  A61K47/14 ,  A61P33/00 ,  A61K38/12

CPC分类号： A61K38/15 ,  A61K9/0017 ,  A61K47/10 ,  A61K47/14 ,  A61K47/22 ,  A61K47/38

摘要： The invention relates to endoparasiticidal agents which can be applied topically. Said agents contain cyclic and open-chained depsipeptides consisting of amino acids and hydroxycarboxylic acids as the components and containing between 6 and 30 ring or chain atoms. The invention also relates to the production of said agents and to their use as endoparasiticides.