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公开(公告)号：EP1525202B1
公开(公告)日：2006-01-11
申请号：EP03764943.1
申请日：2003-07-07
申请人： Bayer HealthCare AG
发明人： FEURER, Achim , LUITHLE, Joachim , WIRTZ, Stephan-Nicholas , KÖNIG, Gerhard , STASCH, Johannes-Peter , STAHL, Elke , SCHREIBER, Rudy , WUNDER, Frank , LANG, Dieter
IPC分类号： C07D471/04 , A61K31/506 , A61P25/00
CPC分类号： C07D471/04
摘要： The invention relates to novel 2,5-disubstituted pyrimidine derivatives, which stimulate the soluble guanylate cyclase, method for production and use thereof for the production of medicaments, in particular medicaments for the treatment of central nervous system diseases.
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公开(公告)号：EP1525203A1
公开(公告)日：2005-04-27
申请号：EP03740426.6
申请日：2003-07-07
申请人： Bayer HealthCare AG
发明人： FEURER, Achim , LUITHLE, Joachim , WIRTZ, Stephan-Nicholas , KÖNIG, Gerhard , STASCH, Johannes-Peter , STAHL, Elke , SCHREIBER, Rudy , WUNDER, Frank , LANG, Dieter
IPC分类号： C07D471/04 , A61K31/505 , A61P25/28
CPC分类号： C07D471/04
摘要： The invention relates to novel 4-amino-substituted pyrimidine derivatives, which stimulate soluble guanylate cyclase, method for production and use thereof for the production of medicaments, in particular medicaments for the treatment of diseases of the central nervous system.
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公开(公告)号：EP1525202A1
公开(公告)日：2005-04-27
申请号：EP03764943.1
申请日：2003-07-07
申请人： Bayer HealthCare AG
发明人： FEURER, Achim , LUITHLE, Joachim , WIRTZ, Stephan-Nicholas , KÖNIG, Gerhard , STASCH, Johannes-Peter , STAHL, Elke , SCHREIBER, Rudy , WUNDER, Frank , LANG, Dieter
IPC分类号： C07D471/00 , A61K31/00 , A61P25/00
CPC分类号： C07D471/04
摘要： The invention relates to novel 2,5-disubstituted pyrimidine derivatives, which stimulate the soluble guanylate cyclase, method for production and use thereof for the production of medicaments, in particular medicaments for the treatment of central nervous system diseases.
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公开(公告)号：EP1546147A1
公开(公告)日：2005-06-29
申请号：EP03757849.9
申请日：2003-09-16
申请人： Bayer HealthCare AG
发明人： FEURER, Achim , LUITHLE, Joachim , WIRTZ, Stephan-Nicholas , KÖNIG, Gerhard , STASCH, Johannes-Peter , WUNDER, Frank , LANG, Dieter , STAHL, Elke , SCHENKE, Thomas , SCHREIBER, Rudy
IPC分类号： C07D471/04 , A61K31/5386 , A61P25/28
CPC分类号： C07D471/04
摘要： The invention relates to novel morpholine-bridged indazole derivatives which stimulate soluble guanylate cyclase, to methods for the production thereof and to the use of the same for producing medicaments, especially medicaments for treating diseases of the central nervous system.
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5.发明授权
公开(公告)号：EP1432686B1
公开(公告)日：2005-06-29
申请号：EP02767480.3
申请日：2002-09-11
申请人： Bayer HealthCare AG
IPC分类号： C07D221/26 , C07D401/12 , A61K31/47 , A61K31/495 , A61P25/04 , A61P29/00
CPC分类号： C07D401/12 , C07D217/26
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6.发明公开
公开(公告)号：EP1432686A1
公开(公告)日：2004-06-30
申请号：EP02767480.3
申请日：2002-09-11
申请人： Bayer HealthCare AG
IPC分类号： C07D221/26 , C07D401/12 , A61K31/47 , A61K31/495 , A61P25/04 , A61P29/00
CPC分类号： C07D401/12 , C07D217/26
摘要： The invention relates to novel tetrahydroisochinolines according to formula (I), to methods for the production thereof and to their use for producing medicaments that are used in the treatment and/or prophylaxis of illnesses, particularly conditions of pain.
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