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1.发明授权Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers 有权Arylharnstoffverbindungen在与其他细胞生长抑制剂或细胞毒性药物联合用于人类治疗癌症
公开(公告)号：EP1769795B1
公开(公告)日：2013-07-24
申请号：EP06023696.5
申请日：2002-12-03
申请人： Bayer HealthCare LLC
发明人： Carter, Christopher A. , Gibson, Neil , Hibner, Barbara , Humphrey, Rachel W. , Trail, Pamela , Vincent, Patrick W. , Zhai, Yifan
IPC分类号： A61K31/44 , A61K31/535 , A61K31/65 , A61K31/435 , A61K31/505 , A61K31/47
CPC分类号： C07D213/81 , A61K31/337 , A61K31/435 , A61K31/44 , A61K31/4412 , A61K31/47 , A61K31/4745 , A61K31/505 , A61K31/513 , A61K31/535 , A61K31/65 , A61K31/704 , A61K31/7072 , A61K45/06 , A61K2300/00
摘要： This invention relates to aryl urea compounds in combination with cytotoxic or cytostatic agents for use in treating raf kinase mediated diseases such as cancer
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2.发明公开Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers 有权芳基脲化合物与其他细胞抑制剂或细胞毒剂组合用于治疗人类癌症
公开(公告)号：EP2305255A1
公开(公告)日：2011-04-06
申请号：EP10183659.1
申请日：2002-12-03
申请人： Bayer HealthCare LLC
发明人： Carter, Christopher A. , Gibson, Neil , Hibner, Barbara , Humphrey, Rachel W. , Trail, Pamela , Vincent, Patrick , Zhai, Yifan
IPC分类号： A61K31/44 , A61K31/535 , A61K31/65 , A61K31/435 , A61K31/505 , A61K31/47 , A61P35/00
CPC分类号： C07D213/81 , A61K31/337 , A61K31/435 , A61K31/44 , A61K31/4412 , A61K31/47 , A61K31/4745 , A61K31/505 , A61K31/513 , A61K31/535 , A61K31/65 , A61K31/704 , A61K31/7072 , A61K45/06 , A61K2300/00
摘要： This invention relates to aryl urea compounds in combination with cytotoxic or cytostatic agents for use in treating raf kinase mediated diseases such as cancer.
摘要翻译： 本发明涉及与用于治疗raf激酶介导的疾病（如癌症）的细胞毒素或细胞抑制剂组合的芳基脲化合物。
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3.发明授权Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers 有权在组合的芳基脲化合物对人类癌症的治疗其它细胞抑制或细胞毒性活性物质
公开(公告)号：EP2295057B1
公开(公告)日：2013-01-23
申请号：EP10183680.7
申请日：2002-12-03
申请人： Bayer HealthCare LLC
发明人： Carter, Christopher A. , Gibson, Neil , Hibner, Barbara , Humphrey, Rachel W. , Trail, Pamela , Vincent, Patrick , Zhai, Yifan
IPC分类号： A61K31/44 , A61K31/535 , A61K31/65 , A61K31/435 , A61K31/505 , A61K31/47 , A61P35/00
CPC分类号： C07D213/81 , A61K31/337 , A61K31/435 , A61K31/44 , A61K31/4412 , A61K31/47 , A61K31/4745 , A61K31/505 , A61K31/513 , A61K31/535 , A61K31/65 , A61K31/704 , A61K31/7072 , A61K45/06 , A61K2300/00
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4.发明授权Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers 有权在组合的芳基脲化合物对人类癌症的治疗其它细胞抑制或细胞毒性活性物质
公开(公告)号：EP2305255B1
公开(公告)日：2012-08-22
申请号：EP10183659.1
申请日：2002-12-03
申请人： Bayer HealthCare LLC
发明人： Carter, Christopher A. , Gibson, Neil , Hibner, Barbara , Humphrey, Rachel W. , Trail, Pamela , Vincent, Patrick , Zhai, Yifan
IPC分类号： A61K31/44 , A61K31/535 , A61K31/65 , A61K31/435 , A61K31/505 , A61K31/47 , A61P35/00
CPC分类号： C07D213/81 , A61K31/337 , A61K31/435 , A61K31/44 , A61K31/4412 , A61K31/47 , A61K31/4745 , A61K31/505 , A61K31/513 , A61K31/535 , A61K31/65 , A61K31/704 , A61K31/7072 , A61K45/06 , A61K2300/00
摘要： This invention relates to aryl urea compounds in combination with cytotoxic or cytostatic agents for use in treating raf kinase mediated diseases such as cancer
摘要翻译： 本发明涉及芳基与用于使用细胞毒性或细胞抑制剂组合的脲化合物治疗RAF激酶介导的疾病：如癌症
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5.发明公开Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers 有权在组合的芳基脲化合物对人类癌症的治疗其它细胞抑制或细胞毒性活性物质
公开(公告)号：EP2295057A1
公开(公告)日：2011-03-16
申请号：EP10183680.7
申请日：2002-12-03
申请人： Bayer HealthCare LLC
发明人： Carter, Christopher A. , Gibson, Neil , Hibner, Barbara , Humphrey, Rachel W. , Trail, Pamela , Vincent, Patrick , Zhai, Yifan
IPC分类号： A61K31/44 , A61K31/535 , A61K31/65 , A61K31/435 , A61K31/505 , A61K31/47 , A61P35/00
CPC分类号： C07D213/81 , A61K31/337 , A61K31/435 , A61K31/44 , A61K31/4412 , A61K31/47 , A61K31/4745 , A61K31/505 , A61K31/513 , A61K31/535 , A61K31/65 , A61K31/704 , A61K31/7072 , A61K45/06 , A61K2300/00
摘要： This invention relates to aryl urea compounds in combination with cytotoxic or cytostatic agents for use in treating raf kinase mediated diseases such as cancer.
摘要翻译： 本发明涉及芳基与细胞毒性或细胞生长抑制剂的组合产品脲化合物治疗Raf激介导的疾病：如癌症。
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6.发明授权Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers 有权在组合的芳基脲化合物对人类癌症的治疗其它细胞抑制或细胞毒性活性物质
公开(公告)号：EP2305256B1
公开(公告)日：2012-10-24
申请号：EP10183700.3
申请日：2002-12-03
申请人： Bayer HealthCare LLC
发明人： Carter, Christopher A. , Gibson, Neil , Hibner, Barbara , Humphrey, Rachel W. , Trail, Pamela , Vincent, Patrick , Zhai, Yifan
IPC分类号： A61K31/44 , A61K31/535 , A61K31/65 , A61K31/435 , A61K31/505 , A61K31/47 , A61P35/00
CPC分类号： C07D213/81 , A61K31/337 , A61K31/435 , A61K31/44 , A61K31/4412 , A61K31/47 , A61K31/4745 , A61K31/505 , A61K31/513 , A61K31/535 , A61K31/65 , A61K31/704 , A61K31/7072 , A61K45/06 , A61K2300/00
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7.发明公开Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers 有权在组合的芳基脲化合物对人类癌症的治疗其它细胞抑制或细胞毒性活性物质
公开(公告)号：EP2305256A1
公开(公告)日：2011-04-06
申请号：EP10183700.3
申请日：2002-12-03
申请人： Bayer Healthcare LLC
发明人： Carter, Christopher A. , Gibson, Neil , Hibner, Barbara , Humphrey, Rachel W. , Trail, Pamela , Vincent, Patrick , Zhai, Yifan
IPC分类号： A61K31/44 , A61K31/535 , A61K31/65 , A61K31/435 , A61K31/505 , A61K31/47 , A61P35/00
CPC分类号： C07D213/81 , A61K31/337 , A61K31/435 , A61K31/44 , A61K31/4412 , A61K31/47 , A61K31/4745 , A61K31/505 , A61K31/513 , A61K31/535 , A61K31/65 , A61K31/704 , A61K31/7072 , A61K45/06 , A61K2300/00
摘要： This invention relates to aryl urea compounds in combination with cytotoxic or cytostatic agents for use in treating raf kinase mediated diseases such as cancer.
摘要翻译： 本发明涉及芳基与细胞毒性或细胞生长抑制剂的组合产品脲化合物治疗Raf激介导的疾病：如癌症。
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