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公开(公告)号：EP2802588B1
公开(公告)日：2016-05-25
申请号：EP13700987.4
申请日：2013-01-08
发明人： BÄRFACKER, Lars , SCOTT, William , HÄGEBARTH, Andreas , REHWINKEL, Hartmut , POLITZ, Oliver , NEUHAUS, Roland , BÖMER, Ulf
IPC分类号： A61K45/06
CPC分类号： A61K31/519 , A61K45/06 , C07D487/04
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公开(公告)号：EP2802586B1
公开(公告)日：2016-05-25
申请号：EP13700139.2
申请日：2013-01-08
发明人： BÄRFACKER, Lars , SCOTT, William , HÄGEBARTH, Andrea , INCE, Stuart , REHWINKEL, Hartmut , POLITZ, Oliver , NEUHAUS, Roland , BÖMER, Ulf
IPC分类号： A61K45/06
CPC分类号： C07D487/04 , A61K31/4985 , A61K45/06 , A61K2300/00
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公开(公告)号：EP2598505A2
公开(公告)日：2013-06-05
申请号：EP11737952.9
申请日：2011-07-27
IPC分类号： C07D487/04 , A61K31/5025
CPC分类号： C07D487/04
摘要： The invention relates to imidazo[1,2-b]pyridazines of general formula (I) a process for their manufacuture and their use for the treatment of benign and malignant neoplasia.
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4.发明授权SUBSTITUTED PYRIMIDO[1,2-B]INDAZOLES AND THEIR USE AS MODULATORS OF THE PI3K/AKT PATHWAY 有权取代的嘧啶并[1,2-B]吲唑及其作为PI3K / AKT信号路径的调节剂
公开(公告)号：EP2651949B1
公开(公告)日：2015-07-15
申请号：EP11796996.4
申请日：2011-12-13
IPC分类号： C07D487/04 , A61K31/519 , A61P35/00
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06
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公开(公告)号：EP2598505B1
公开(公告)日：2015-03-18
申请号：EP11737952.9
申请日：2011-07-27
IPC分类号： C07D487/04 , A61K31/5025 , A61P35/00
CPC分类号： C07D487/04
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公开(公告)号：EP2593458A1
公开(公告)日：2013-05-22
申请号：EP11736032.1
申请日：2011-07-11
发明人： INCE, Stuart , REHWINKEL, Hartmut , HAEGEBARTH, Andrea , POLITZ, Oliver , NEUHAUS, Roland , BÖMER, Ulf
IPC分类号： C07D487/04 , A61K31/519 , A61P35/00
CPC分类号： A61K31/5377 , A61K31/519 , A61K45/06 , C07D487/04
摘要： Compounds of formula (I), which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
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公开(公告)号：EP2802588A1
公开(公告)日：2014-11-19
申请号：EP13700987.4
申请日：2013-01-08
发明人： BÄRFACKER, Lars , SCOTT, William , HÄGEBARTH, Andreas , REHWINKEL, Hartmut , POLITZ, Oliver , NEUHAUS, Roland , BÖMER, Ulf
IPC分类号： C07D487/04 , A61K31/519 , A61P35/00
CPC分类号： A61K31/519 , A61K45/06 , C07D487/04
摘要： Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
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公开(公告)号：EP2694510A1
公开(公告)日：2014-02-12
申请号：EP12713963.2
申请日：2012-04-05
发明人： BÄRFACKER, Lars , SCOTT, William Johnston , HÄGEBARTH, Andrea , INCE, Stuart , REHWINKEL, Hartmut , POLITZ, Oliver , NEUHAUS, Roland , BRIEM, Hans , BÖMER, Ulf
IPC分类号： C07D487/04 , A61K31/5025 , A61P35/00
CPC分类号： C07D487/04 , A61K31/5025 , A61K45/06
摘要： Imidazopyridazines of formula (I) a process for their production and the use thereof.
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9.发明公开SUBSTITUTED PYRIMIDO[1,2-B]INDAZOLES AND THEIR USE AS MODULATORS OF THE PI3K/AKT PATHWAY 有权取代的嘧啶并[1,2-B]吲唑及其作为PI3K / AKT信号路径的调节剂
公开(公告)号：EP2651949A1
公开(公告)日：2013-10-23
申请号：EP11796996.4
申请日：2011-12-13
IPC分类号： C07D487/04 , A61K31/519 , A61P35/00
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06
摘要： Compounds of Formula (I), which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals. The compounds of formula (I) a: useful for the treatment of cancer.
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公开(公告)号：EP2694510B1
公开(公告)日：2015-10-14
申请号：EP12713963.2
申请日：2012-04-05
发明人： BÄRFACKER, Lars , SCOTT, William Johnston , HÄGEBARTH, Andrea , INCE, Stuart , REHWINKEL, Hartmut , POLITZ, Oliver , NEUHAUS, Roland , BRIEM, Hans , BÖMER, Ulf
IPC分类号： C07D487/04 , A61K31/5025 , A61P35/00
CPC分类号： C07D487/04 , A61K31/5025 , A61K45/06
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