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1.发明公开3-AMINO-PYRAZOLO[3,4B]PYRIDINE ALS INHIBITOREN VON PROTEINTYROSINKINASEN ZUR BEHANDLUNG VON ANGIOGENEN, HYPERPROLIFERATIVEN ODER NEURODEGENERATIVEN ERKRANKUNGEN 有权3-氨基吡唑并[3,4-b]吡啶作为蛋白激酶用于治疗血管生成过度增殖性或神经变性疾病的抑制剂
公开(公告)号：EP1846402A1
公开(公告)日：2007-10-24
申请号：EP05821901.5
申请日：2005-12-12
发明人： SCHWEDE, Wolfgang , KÜNZER, Hermann , TER LAAK, Antonius , BADER, Benjamin , HILLIG, Roman , MÖNNING, Ursula , SCHMITZ, Arndt , ZOPF, Dieter
IPC分类号： C07D471/04 , A61K31/437 , A61P35/00 , A61P9/10 , A61P25/28
CPC分类号： C07D471/04 , C07D213/85
摘要： The invention relates to compounds of general formula (I), in which R1 and R2 are described in the application, to the use of the compounds of general formula (I) as inhibitors of protein tyrosine kinases for treating various diseases, and to the compounds of general formulas (II) and (III) as intermediate compounds for producing compounds of general formula (I), in which X, R1a and R2a have the meanings as described in general formulas (II) and (III).
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2.发明公开CHINOLINDERIVAT, DESSEN VERWENDUNG, HERSTELLUNG UND DIESES ENTHALTENDES ARZNEIMITTEL 有权喹啉衍生物，它的使用，生产和这种含药物
公开(公告)号：EP1833830A1
公开(公告)日：2007-09-19
申请号：EP05850343.4
申请日：2005-12-19
发明人： SCHWEDE, Wolfgang , JAROCH, Stefan , BADER, Benjamin , HILLIG, Roman , TER LAAK, Antonius , ZOPF, Dieter
IPC分类号： C07D471/04 , A61K31/435 , A61P35/00
CPC分类号： C07D221/06 , C07D471/04 , C07D491/04 , C07D495/04 , C07D498/04 , C07D513/04
摘要： The invention relates to a quinoline derivative of general formula (A), wherein R1, R2, R3, X, Y, Z and A are defined as in the description and the claims. The invention also relates to the use of the compounds of general formula (A) in the treatment of various diseases and to the production of the compounds of general formula (A).
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3.发明授权CHINOLINDERIVAT, DESSEN VERWENDUNG, HERSTELLUNG UND DIESES ENTHALTENDES ARZNEIMITTEL 有权喹啉衍生物，它的使用，生产和这种含药物
公开(公告)号：EP1833830B1
公开(公告)日：2009-10-14
申请号：EP05850343.4
申请日：2005-12-19
发明人： SCHWEDE, Wolfgang , JAROCH, Stefan , BADER, Benjamin , HILLIG, Roman , TER LAAK, Antonius , ZOPF, Dieter
IPC分类号： C07D471/04 , A61K31/435 , A61P35/00
CPC分类号： C07D221/06 , C07D471/04 , C07D491/04 , C07D495/04 , C07D498/04 , C07D513/04
摘要： The invention relates to a quinoline derivative of general formula (A), wherein R1, R2, R3, X, Y, Z and A are defined as in the description and the claims. The invention also relates to the use of the compounds of general formula (A) in the treatment of various diseases and to the production of the compounds of general formula (A).
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