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1.发明授权CHINOLINDERIVAT, DESSEN VERWENDUNG, HERSTELLUNG UND DIESES ENTHALTENDES ARZNEIMITTEL 有权喹啉衍生物，它的使用，生产和这种含药物
公开(公告)号：EP1833830B1
公开(公告)日：2009-10-14
申请号：EP05850343.4
申请日：2005-12-19
发明人： SCHWEDE, Wolfgang , JAROCH, Stefan , BADER, Benjamin , HILLIG, Roman , TER LAAK, Antonius , ZOPF, Dieter
IPC分类号： C07D471/04 , A61K31/435 , A61P35/00
CPC分类号： C07D221/06 , C07D471/04 , C07D491/04 , C07D495/04 , C07D498/04 , C07D513/04
摘要： The invention relates to a quinoline derivative of general formula (A), wherein R1, R2, R3, X, Y, Z and A are defined as in the description and the claims. The invention also relates to the use of the compounds of general formula (A) in the treatment of various diseases and to the production of the compounds of general formula (A).
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2.发明公开
公开(公告)号：EP2041069A1
公开(公告)日：2009-04-01
申请号：EP07786221.7
申请日：2007-07-16
IPC分类号： C07C215/16 , C07D215/38 , A61K31/136 , C07D401/12 , C07D405/14 , C07D405/12 , C07C217/78
CPC分类号： C07C215/16 , C07B2200/07 , C07C215/28 , C07C217/70 , C07C317/28 , C07D215/38 , C07D233/84 , C07D401/12 , C07D405/12 , C07D405/14
摘要： The present invention relates to the compounds of formula (I), processes for their production and their use as anti-inflammatory agents.
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3.发明授权5-SUBSTITUIERTE CHINOLIN- UND ISOCHINOLIN-DERIVATE; EIN VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ENTZÜNDUNGSHEMMER 有权5-取代的喹啉和异喹啉衍生物; 其制备方法及其用作抗抑制剂
公开(公告)号：EP1844039B1
公开(公告)日：2009-07-15
申请号：EP05808294.2
申请日：2005-11-11
发明人： JAROCH, Stefan , REHWINKEL, Hartmut , SCHÄCKE, Heike , SCHMEES, Norbert , SKUBALLA, Werner , SCHNEIDER, Matthias , HÜBNER, Jan , PETROV, Orlin , DINTER, Christian
IPC分类号： C07D405/12 , C07D307/79 , C07D307/83 , C07C69/68 , A61K31/47 , A61P29/00
CPC分类号： C07D307/79 , C07C69/732 , C07C69/734 , C07D307/83 , C07D405/12
摘要： The invention relates to compounds of general formulas (IIa) or (IIb) and to their use as medicaments.
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4.发明授权
公开(公告)号：EP1282610B1
公开(公告)日：2007-07-25
申请号：EP01929561.7
申请日：2001-04-12
发明人： REHWINKEL, Hartmut , HÖLSCHER, Peter , JAROCH, Stefan , SÜLZLE, Detlev , HILLMANN, Margrit , BURTON, Gerardine, Anne , MCDONALD, Fiona, Mcdougall
IPC分类号： C07D265/36 , C07D265/34 , A61K31/538
CPC分类号： C07D265/36 , C07D265/34
摘要： The invention relates to the compounds of formula (I), to the tautomers and isomers and salts thereof, and to a method for producing the same as well as to the use thereof in medicaments.
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5.发明公开CHINOLINDERIVAT, DESSEN VERWENDUNG, HERSTELLUNG UND DIESES ENTHALTENDES ARZNEIMITTEL 有权喹啉衍生物，它的使用，生产和这种含药物
公开(公告)号：EP1833830A1
公开(公告)日：2007-09-19
申请号：EP05850343.4
申请日：2005-12-19
发明人： SCHWEDE, Wolfgang , JAROCH, Stefan , BADER, Benjamin , HILLIG, Roman , TER LAAK, Antonius , ZOPF, Dieter
IPC分类号： C07D471/04 , A61K31/435 , A61P35/00
CPC分类号： C07D221/06 , C07D471/04 , C07D491/04 , C07D495/04 , C07D498/04 , C07D513/04
摘要： The invention relates to a quinoline derivative of general formula (A), wherein R1, R2, R3, X, Y, Z and A are defined as in the description and the claims. The invention also relates to the use of the compounds of general formula (A) in the treatment of various diseases and to the production of the compounds of general formula (A).
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6.发明公开
公开(公告)号：EP1786823A1
公开(公告)日：2007-05-23
申请号：EP05786302.9
申请日：2005-09-02
发明人： BÄURLE, Stefan , BERGER, Markus , JAROCH, Stefan , KROLIKIEWICZ, Konrad , NGUYEN, Duy , REHWINKEL, Hartmut , SCHÄCKE, Heike , SCHMEES, Norbert , SKUBALLA, Werner
IPC分类号： C07F5/02 , C07D215/38 , C07D215/22 , C07D237/32 , C07D239/84 , C07C69/02 , A61K31/4704 , A61K31/517 , A61K31/502 , A61P29/00
CPC分类号： C07D215/227 , C07C69/734 , C07D215/38 , C07D237/32 , C07D239/84
摘要： The invention relates to alkylidene tetrahydronaphthalene derivatives of general formula (I), to methods for their production and to their use as anti-inflammatory agents.
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7.发明授权
公开(公告)号：EP1786823B1
公开(公告)日：2008-01-16
申请号：EP05786302.9
申请日：2005-09-02
发明人： BÄURLE, Stefan , BERGER, Markus , JAROCH, Stefan , KROLIKIEWICZ, Konrad , NGUYEN, Duy , REHWINKEL, Hartmut , SCHÄCKE, Heike , SCHMEES, Norbert , SKUBALLA, Werner
IPC分类号： C07F5/02 , C07D215/38 , C07D215/22 , C07D237/32 , C07D239/84 , C07C69/02 , A61K31/4704 , A61K31/517 , A61K31/502 , A61P29/00
CPC分类号： C07D215/227 , C07C69/734 , C07D215/38 , C07D237/32 , C07D239/84
摘要： The invention relates to alkylidene tetrahydronaphthalene derivatives of general formula (I), to methods for their production and to their use as anti-inflammatory agents.
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8.发明公开5-SUBSTITUIERTE CHINOLIN- UND ISOCHINOLIN-DERIVATE; EIN VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ENTZÜNDUNGSHEMMER 有权5-取代的喹啉和异喹啉衍生物; 其制备方法及其用作抗抑制剂
公开(公告)号：EP1844039A1
公开(公告)日：2007-10-17
申请号：EP05808294.2
申请日：2005-11-11
发明人： JAROCH, Stefan , REHWINKEL, Hartmut , SCHÄCKE, Heike , SCHMEES, Norbert , SKUBALLA, Werner , SCHNEIDER, Matthias , HÜBNER, Jan , PETROV, Orlin , DINTER, Christian
IPC分类号： C07D405/12 , C07D307/79 , C07D307/83 , C07C69/68 , A61K31/47 , A61P29/00
CPC分类号： C07D307/79 , C07C69/732 , C07C69/734 , C07D307/83 , C07D405/12
摘要： The invention relates to compounds of general formulas (IIa) or (IIb) and to their use as medicaments.
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