公开(公告)号：EP1742945B1

公开(公告)日：2009-12-30

申请号：EP05739438.9

申请日：2005-04-14

申请人： Bayer Schering Pharma Aktiengesellschaft

发明人： SCHIROK, Hartmut ,  STASCH, Johannes-Peter ,  KAST, Raimund ,  MÜNTER, Klaus ,  GNOTH, Mark, Jean ,  FIGUEROA, PEREZ, Santiago ,  THUTEWOHL, Michael ,  BENNABI, Samir ,  LANG, Dieter ,  MITTENDORF, Joachim ,  RADTKE, Martin ,  EHMKE, Heimo c/o Universität Hamburg

IPC分类号： C07D471/04 ,  A61K31/437 ,  A61P9/10

CPC分类号： C07D471/04

摘要： The invention relates to substituted phenylamino-pyrimidines, to a method for their production and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular for the treatment of cardiovascular diseases.

公开(公告)号：EP2297099A1

公开(公告)日：2011-03-23

申请号：EP09768940.0

申请日：2009-06-18

申请人： Bayer Schering Pharma Aktiengesellschaft

发明人： THEDE, Kai ,  WOLTERING, Elisabeth ,  KOLKHOF, Peter ,  SCHMECK, Carsten ,  POOK, Elisabeth ,  HILLISCH, Alexander ,  BÄRFACKER, Lars ,  LUSTIG, Klemens ,  LANG, Dieter ,  RADTKE, Martin ,  GROSSER, Rolf ,  BRÜNS, Astrid ,  GERISCH, Michael

IPC分类号： C07D209/10 ,  C07D487/04 ,  A61K31/40

CPC分类号： C07D209/10 ,  C07D487/04

摘要： The present application relates to novel 3-cyanoalkyl- and 3-hydroxyalkyl-substituted indole derivatives, to processes for preparation thereof, to the use thereof alone or in combination for treatment and/or prevention of disorders, and to the use thereof for production of medicaments for treatment and/or prevention of disorders, especially for treatment and/or prevention of cardiovascular disorders.