CARNITIN ENTHALTENDE KOSMETISCHE UND DERMATOLOGISCHE ZUBEREITUNGEN ZUR BEHANDLUNG UND AKTIVEN PRÄVENTION TROCKENER HAUT UND ANDERER NEGATIVER VERÄNDERUNGEN DER PHYSIOLOGISCHEN HOMÖOSTASE DER GESUNDEN HAUT
    3.
    发明公开
    CARNITIN ENTHALTENDE KOSMETISCHE UND DERMATOLOGISCHE ZUBEREITUNGEN ZUR BEHANDLUNG UND AKTIVEN PRÄVENTION TROCKENER HAUT UND ANDERER NEGATIVER VERÄNDERUNGEN DER PHYSIOLOGISCHEN HOMÖOSTASE DER GESUNDEN HAUT 审中-公开
    含肉碱化妆品和皮肤病筹备工作生理内环境稳定健康的皮肤治疗和皮肤干燥等负面变化的积极预防

    公开(公告)号:EP1406586A2

    公开(公告)日:2004-04-14

    申请号:EP02762320.6

    申请日:2002-07-04

    申请人: Beiersdorf AG

    IPC分类号: A61K7/48 A61K7/06 A61K31/205

    摘要: The invention relates to the use of preparations that are to be topically applied containing a) one compound or several compounds from the group consisting of carnitine and its precursors, derivatives and metabolites, b) optionally one compound or several compounds from the group of electrolytes c) optionally one compound or several compounds from the group of polyols and urea and optionally d) one compound or several compounds from the group of osmolytes, for treating and actively preventing dry skin and for reinforcing the barrier function of the skin. Said preparations are also used for the treatment, care and prophylaxis of sensitive skin and/or for the treatment and prophylaxis of the following symptoms of a negative alteration in the physiological homeostasis of healthy skin.

    摘要翻译: 含肉碱的局部组合物及其前体,衍生物或代谢物于,如使用 改善皮肤状况或用于治疗或预防皮肤疾病,异常脂质过氧化,减少的细胞 - 细胞通讯,缺陷细胞内DNA合成,DNA损伤,DNA修复缺陷型,结缔组织成分或头皮屑的异常翻译后修饰。 局部用组合物包括肉碱和其前体,衍生物或代谢产物和任选的电解质,多元醇,尿素和渗压剂被使用:(1)用于治疗或预防皮肤干燥,以增强皮肤的屏障功能,用于治疗,护理和的敏感预防 皮肤和/或用于治疗和在正常皮肤的生理平衡的负变化的预防症状; (2)用于治疗或预防炎性皮肤病症,特应性湿疹,多态照片皮炎,牛皮癣,白癜风和敏感,瘙痒或刺激的皮肤; (3)用于治疗或预防异常脂质过氧化; (4)用于治疗或预防异常神经酰胺,脂和皮肤的能量代谢,经皮水分流失异常,降低的皮肤水化和水分含量和改变的天然保湿因子的内容; (5)以治疗或预防降低的细胞间通讯,缺陷细胞内DNA合成,DNA损伤,降低内源性DNA修复,金属蛋白酶和/或其他蛋白酶或相应的DNA修复机制和结缔组织的异常翻译后修饰的抑制活化 组件; (6)用于治疗或预防异常皮肤透明质酸和葡糖胺聚糖含量; (七)以治疗或预防头发和头皮和皮肤老化的头皮屑。