公开(公告)号：EP4332087A1

公开(公告)日：2024-03-06

申请号：EP23163495.7

申请日：2023-03-22

申请人： Beijing Jitai Pharmaceutical Technology Co., Ltd. ,  Hangzhou Jitai Pharmaceutical Technology Co., Ltd.

发明人： YANG, Liu ,  YIN, Le ,  LIU, Andong ,  ZHANG, Lin ,  LAI, Caida ,  WANG, Wenshou

IPC分类号： C07C229/12 ,  A61K9/00 ,  C07D207/08 ,  C12N15/11 ,  C07D211/08 ,  C07D211/16 ,  C07D223/04 ,  C07D265/30 ,  A61K9/51 ,  C07C235/06 ,  C07C271/22 ,  C07C275/16 ,  C07C327/22 ,  C07C329/06

摘要： The present disclosure provides a lipid nanoparticle wherein the lipid ingredient comprises a compound of formula (IV). The present disclosure also provides a method of preparing the lipid nanoparticle, a pharmaceutical composition of the lipid nanoparticle, and use of the lipid nanoparticle and pharmaceutical compositions in the delivery of nucleic acids.