专利检索 ap:("BioMarin Pharmaceutical Inc.") AND inv:"Price, Fredric D." 第 1 页

1.

发明公开
TREATMENT OF PHENYLKETONURIA WITH BH4 审中-公开

公开(公告)号：EP3977999A1

公开(公告)日：2022-04-06

申请号：EP21209606.9

申请日：2004-11-17

申请人： BioMarin Pharmaceutical Inc.

发明人： Oppenheimer, Daniel I. , Kakkis, Emil, D. , Price, Fredric D. , Dorenbaum, Alejandro

IPC分类号： A61K31/519 , A61P3/00

摘要： The present invention is directed to novel methods and compositions for the therapeutic intervention in hyperphenylalaninemia. More specifically, the specification describes compositions comprising tetrahydrobiopterin (BH4) and the use thereof in methods of treating various types of phenylketonurias. Combination therapies of BH4 and other therapeutic regimens are contemplated.