公开(公告)号：EP4253571A3

公开(公告)日：2023-12-13

申请号：EP23186579.1

申请日：2020-11-06

申请人： Biogaia AB

发明人： GRASSET, Estelle ,  KHAN, Muhammad ,  MÖLLSTAM, Bo ,  ROOS, Stefan

IPC分类号： A61P25/00 ,  A23L33/135 ,  A61K35/747 ,  C12N1/20 ,  C12R1/225 ,  C12R1/25

摘要： The invention relates to selection of bacterial strain for use in treating a disease related to serotonin deficiency by culturing bacteria of a lactic acid producing bacterial strain, under aerobic conditions, in a culture medium comprising tryptophan. Any serotonin produced by the bacteria of the lactic acid producing bacterial strain in the culture medium is detected and the lactic acid producing bacterial strain is selected as effective in treating serotonin deficiency and/or a disease related to serotonin deficiency in a subject if serotonin is detected in the culture medium.

公开(公告)号：EP3897836A1

公开(公告)日：2021-10-27

申请号：EP20807535.8

申请日：2020-11-06

申请人： Biogaia AB

发明人： GRASSET, Estelle ,  KHAN, Muhammad ,  MÖLLSTAM, Bo ,  ROOS, Stefan

IPC分类号： A61P25/00 ,  A23L33/135 ,  A61K35/747 ,  C12N1/20 ,  C12R1/225 ,  C12R1/25

公开(公告)号：EP4253571A2

公开(公告)日：2023-10-04

申请号：EP23186579.1

申请日：2020-11-06

申请人： Biogaia AB

发明人： GRASSET, Estelle ,  KHAN, Muhammad ,  MÖLLSTAM, Bo ,  ROOS, Stefan

IPC分类号： C12R1/25

摘要： The invention relates to selection of bacterial strain for use in treating a disease related to serotonin deficiency by culturing bacteria of a lactic acid producing bacterial strain, under aerobic conditions, in a culture medium comprising tryptophan. Any serotonin produced by the bacteria of the lactic acid producing bacterial strain in the culture medium is detected and the lactic acid producing bacterial strain is selected as effective in treating serotonin deficiency and/or a disease related to serotonin deficiency in a subject if serotonin is detected in the culture medium.