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1.发明公开
公开(公告)号：EP2379752A1
公开(公告)日：2011-10-26
申请号：EP10707312.4
申请日：2010-01-18
发明人： CAZALIS, Marie-Angélique , LEPAPE, Alain , MONNERET, Guillaume , MOUGIN, Bruno , PACHOT, Alexandre
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6809 , C12Q1/6886 , C12Q2600/118 , C12Q2600/158
摘要： The present invention relates to a method for determining the likelihood of a patient contracting a nosocomial infection and to a method for determining the prognosis of the course of a septic syndrome in a patient, according to which: a. a biological sample is obtained from the patient and biological material is extracted from the biological sample; b. at least one specific reagent is obtained from an expression construct of at least one target gene selected from target genes S100A9 and S100A8; c. the expression of at least one of the target genes S100A9 and S100A8 is determined, an overexpression relative to a predetermined threshold value indicating the likelihood of contracting a nosocomial infection as well as indicating a poor prognosis of the course of a septic syndrome.
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2.发明授权
公开(公告)号：EP2379752B1
公开(公告)日：2015-09-30
申请号：EP10707312.4
申请日：2010-01-18
发明人： CAZALIS, Marie-Angélique , LEPAPE, Alain , MONNERET, Guillaume , MOUGIN, Bruno , PACHOT, Alexandre
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6809 , C12Q1/6886 , C12Q2600/118 , C12Q2600/158
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3.发明公开
公开(公告)号：EP4133277A1
公开(公告)日：2023-02-15
申请号：EP21723881.5
申请日：2021-04-08
申请人： BIOMÉRIEUX , Bioaster , Hospices Civils de Lyon
发明人： MALLET, François , MONNERET, Guillaume , MOUCADEL, Virginie , PACHOT, Alexandre , PERONNET, Estelle , TEXTORIS, Julien , VENET, Fabienne , RIMMELÉ, Thomas
IPC分类号： G01N33/569 , G01N33/68
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4.发明公开
公开(公告)号：EP4034679A1
公开(公告)日：2022-08-03
申请号：EP20790378.2
申请日：2020-09-25
申请人： BIOMÉRIEUX , Bioaster , Hospices Civils de Lyon
发明人： VACHOT, Laurence , MALLET, François , MONNERET, Guillaume , MOUCADEL, Virginie , PACHOT, Alexandre , PERONNET, Estelle , RIMMELÉ, Thomas , TEXTORIS, Julien , VENET, Fabienne
IPC分类号： C12Q1/6883
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公开(公告)号：EP3295178B1
公开(公告)日：2019-07-10
申请号：EP16729013.9
申请日：2016-05-11
发明人： ALLAOUCHICHE, Bernard , ASEHNOUNE, Karim , DUPIN, Marilyne , FORTIN, Tanguy , GOUEL-CHERON, Aurélie , LARUE-TRIOLET, Audrey , MONNERET, Guillaume , PACHOT, Alexandre , PONS, Sylvie , ROQUILLY, Antoine , VENET, Fabienne
IPC分类号： G01N33/68
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公开(公告)号：EP1802773B1
公开(公告)日：2009-08-26
申请号：EP05810890.3
申请日：2005-10-17
申请人： bioMérieux S.A.
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/158
摘要： The invention concerns a method for diagnosing aspirin intolerance from a patient's biological sample characterized in that it includes the following steps: a) extracting a biological material from the biological sample; b) contacting the biological material with at least one specific reagent selected among specific reagents of target genes including a nucleic sequence having any one of SEQ ID N° 1 to 25; c) determining the expression of at least one of said target genes.
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公开(公告)号：EP1802773A1
公开(公告)日：2007-07-04
申请号：EP05810890.3
申请日：2005-10-17
申请人： bioMérieux S.A.
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/158
摘要： The invention concerns a method for diagnosing aspirin intolerance from a patient's biological sample characterized in that it includes the following steps: a) extracting a biological material from the biological sample; b) contacting the biological material with at least one specific reagent selected among specific reagents of target genes including a nucleic sequence having any one of SEQ ID N° 1 to 25; c) determining the expression of at least one of said target genes.
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