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公开(公告)号：EP4115831A1
公开(公告)日：2023-01-11
申请号：EP22155797.8
申请日：2022-02-09
发明人： RAO, Anand , DATTA, Keshava , NGUYEN, Thanh
摘要： Examples presented herein generally include a catheter and a system configured to deliver electrical pulses for ablation by IRE and methods for constructing and using the same. The catheter and system can further be configured to delivery RF electrical current for thermal ablation interleaved with ablation by IRE, simultaneously with ablation by IRE, and/or separately from ablation by IRE. The catheter can have a linear distal portion with a tip electrode, a middle ring electrode, and a proximal ring electrode. The electrodes be configured in several combinations to provide unipolar ablation, bipolar ablation, and/or a combination thereof.
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公开(公告)号：EP3510956B1
公开(公告)日：2020-11-04
申请号：EP19150938.9
申请日：2019-01-09
发明人： RAO, Anand , SELKEE, Thomas , DATTA, Keshava , NGUYEN, Thanh
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公开(公告)号：EP4382061A1
公开(公告)日：2024-06-12
申请号：EP23215306.4
申请日：2023-12-08
发明人： VU, Audrey , GOO, Audrey Claire , KATO, Robert , PATEL, Amar , NGUYEN, Thanh , RAO, Anand , SUAREZ, Paul , ROSEBERRY, Jacob
CPC分类号： A61B2090/06420160201 , A61B18/1492 , A61B2018/0026720130101 , A61B5/6858 , A61B5/6885
摘要： The disclosed technology includes a medical probe comprising a tubular shaft having a proximal end and a distal end, the tubular shaft extending along a longitudinal axis. The medical probe further comprises an expandable basket assembly coupled to the distal end of the tubular shaft. The basket assembly includes a plurality of electrodes with each electrode of the plurality of electrodes having a lumen therethrough. The basket assembly further includes a plurality of spines extending along the longitudinal axis and configured to bow radially outward from the longitudinal axis when the expandable basket assembly is transitioned from a collapsed form to an expanded form. Each spine includes a proximal and a distal end and a strut passing through the lumen of an electrode. The strut includes a mechanical retainer disposed on the strut to prevent the electrode from sliding proximally or distally along a length of the spine.
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公开(公告)号：EP4122414A1
公开(公告)日：2023-01-25
申请号：EP22194801.1
申请日：2020-04-29
发明人： SELKEE, Thomas , NGUYEN, Thanh , DATTA, Keshava , RAO, Anand , PENDEKANTI, Rajesh , BAR-TAL, Meir , PADILLA, Ricardo
摘要： A catheter is described with an end effector having densely arrayed electrodes on three loops which are arrayed in various planar configurations when the end effector is unconstrained. The end effector has first, second and third loop members, each loop member includes two spines and a connector that connects the two spines to define a loop extending away from a tubular member of the catheter such that the first, second and third loop members are configured so that each connector of each of the first, second and third loop members is in contact with only one connector of the adjacent loop member.
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公开(公告)号：EP4115832A1
公开(公告)日：2023-01-11
申请号：EP22155820.8
申请日：2022-02-09
发明人： RAO, Anand , SELKEE, Thomas , DATTA, Keshava , NGUYEN, Thanh
摘要： A catheter can have a distal circular region that can contract in circumference via manipulation of a pull wire. The circular region can have electrodes distributed around the circumference that are suitable for mapping and/or ablation, and preferably suitable for IRE ablation. The catheter can include a cross-over region near a distal end of a shaft in which elongated elements extend at an angle to the longitudinal axis. The cross-over region can be bounded by an intermediate tube having four lumens and a distal tube having three lumens. The circular region can include structural features to facilitate contraction such as a support member having a preferable bending direction, polymer tubing segments positioned to inhibit bending stress on electrodes, navigation sensors positioned to inhibit bending stress on said sensors and electrodes, and a distal assembly at a distal end of the circular region.
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公开(公告)号：EP3733103A1
公开(公告)日：2020-11-04
申请号：EP20172013.3
申请日：2020-04-29
发明人： SELKEE, Thomas , NGUYEN, Thanh , DATTA, Keshava , RAO, Anand , PENDEKANTI, Rajesh , BAR-TAL, Meir , PADILLA, Ricardo
IPC分类号： A61B18/14 , A61B5/042 , A61B5/0402 , A61B34/20
摘要： A catheter is described with an end effector having densely arrayed electrodes on three loops which are arrayed in various planar configurations when the end effector is unconstrained. The end effector has first, second and third loop members, each loop member includes two spines and a connector that connects the two spines to define a loop extending away from a tubular member of the catheter such that the first, second and third loop members are configured so that each connector of each of the first, second and third loop members is in contact with only one connector of the adjacent loop member.
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公开(公告)号：EP3510956A1
公开(公告)日：2019-07-17
申请号：EP19150938.9
申请日：2019-01-09
发明人： RAO, Anand , SELKEE, Thomas , DATTA, Keshava , NGUYEN, Thanh
摘要： A thermocouple assembly may feature a plurality of temperature sensors formed by thermocouple junctions. The sensors may be disposed within an inner diameter of the tubular element and sealed within the tubular element by thermally conductive material. An air gap may be defined by the thermally conductive material and the interior diameter of the tubular element between each pair of adjacent temperature sensors to improve thermal isolation.
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公开(公告)号：EP3510955A1
公开(公告)日：2019-07-17
申请号：EP19150933.0
申请日：2019-01-09
发明人： RAO, Anand , SELKEE, Thomas , DATTA, Keshava , NGUYEN, Thanh
IPC分类号： A61B18/14
摘要： A thermocouple assembly may feature a plurality of temperature sensors formed by thermocouple junctions. The sensors may be disposed upon a substrate, that has a curvature that biases each of the plurality of temperature sensors in a desired direction.
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公开(公告)号：EP4215140A1
公开(公告)日：2023-07-26
申请号：EP23152458.8
申请日：2023-01-19
发明人： DATA, Keshava , RAO, Anand , NGUYEN, Thanh , SELKEE, Thomas V.
摘要： Wiring is disclosed herein that is configured to supply IRE ablation signals through a catheter body and is resistant against dielectric breakdown, arcing, and noise during ablation. The wiring includes a highly conductive core, a conductive cover surrounding the core that has lower electrical and/or thermal conductivity than the core, and an insulative jacket surrounding the conductive cover. A catheter including such wiring may be suitable for supplying electrical signals to tissue to perform IRE ablation. In some examples, such a catheter can also be suitable for reversible electroporation and/or RF ablation.
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公开(公告)号：EP3829428A1
公开(公告)日：2021-06-09
申请号：EP19773536.8
申请日：2019-07-25
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