专利检索 ap:("Biovitrum AB (publ)") AND inv:"BYSTRÖM, Styrbjörn" 第 1 页

1.

发明公开
ISOXAZOLE DERIVATIVES AS MODULATORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 审中-公开
标题翻译：异恶唑的11-β-羟基TYPE 1调节剂

公开(公告)号：EP2231650A1

公开(公告)日：2010-09-29

申请号：EP09702264.4

申请日：2009-01-16

申请人： Biovitrum AB (publ)

发明人： BYSTRÖM, Styrbjörn , HARALDSSON, Martin , JOHANSSON, Lars , TEJBRANT, Jan

IPC分类号： C07D413/06 , A61K31/454 , A61P27/00

CPC分类号： C07D413/06

摘要： The present invention relates to novel isoxazole compounds of formula (I), and pharmaceutically acceptable salts, solvates, hydrates, geometrical isomers, tautomers, optical isomers or N-oxides thereof, which are modulators of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the preparation of a medicament for the treatment of glaucoma.