专利检索 ap:("Boehringer Ingelheim International GmbH") AND inv:"KRISHNAMURTHY, Dhileep" 第 1 页

1.

发明公开
PROCESS FOR PREPARING A POLYMORPH OF THE CHOLINE SALT OF A PYRIMIDIN-5-YL ACETIC ACID DERIVATIVE 审中-公开
标题翻译：用于生产胆碱的多晶型盐嘧啶-5-基 - 乙酸衍生物

公开(公告)号：EP2504319A1

公开(公告)日：2012-10-03

申请号：EP10782506.9

申请日：2010-11-19

申请人： Boehringer Ingelheim International GmbH

发明人： KRISHNAMURTHY, Dhileep , RODRIGUEZ DEHLI, Juan Manuel , SCHUL, Michael , WANG, Xiao-Jun , YANG, Bing-Shiou

IPC分类号： C07D239/48 , A61K31/505 , A61P11/06

CPC分类号： C07D239/48

摘要： Provided is a process for preparing a choline salt of [4,6-bis(dimethylamino)-2-(4-{ [4- (trifluoromethyl)benzoyl] amino }benzyl)pyrimidin-5-yl] acetic acid. The process of the invention is useful for preparing the salt in purer forms of the salt. Also disclosed is a more pure form of the of choline salt of [4,6-bis(dimethylamino)-2-(4-{ [4- (trifluoromethyl)benzoyl] amino }benzyl)pyrimidin-5-yl] acetic acid.