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1.发明公开
公开(公告)号：EP1682541A1
公开(公告)日：2006-07-26
申请号：EP04791028.6
申请日：2004-10-29
IPC分类号： C07D451/10 , A61K31/46 , A61P11/00
CPC分类号： C07D451/10 , C07D451/06
摘要： The invention provides a method for producing novel tiotropium salts of formula (I), wherein X- represents an anion, said novel tiotropium salts as such, pharmaceutical formulations, containing the salts and the use thereof for producing a medicament for the treatment of respiratory tract diseases, in particular, for the treatment of chronic obstructive pulmonary disease (COPD) and asthma.
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公开(公告)号：EP1682541B1
公开(公告)日：2010-03-10
申请号：EP04791028.6
申请日：2004-10-29
IPC分类号： C07D451/10 , A61K31/46 , A61P11/00
CPC分类号： C07D451/10 , C07D451/06
摘要： The invention provides a method for producing novel tiotropium salts of formula (I), wherein X- represents an anion, said novel tiotropium salts as such, pharmaceutical formulations, containing the salts and the use thereof for producing a medicament for the treatment of respiratory tract diseases, in particular, for the treatment of chronic obstructive pulmonary disease (COPD) and asthma.
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公开(公告)号：EP1497289A1
公开(公告)日：2005-01-19
申请号：EP03746158.9
申请日：2003-04-09
发明人： BANHOLZER, Rolf , MEADE, Christopher, John, Montague , MEISSNER, Helmut , MORSCHHÄUSER, Gerd , PAIRET, Michel , PIEPER, Michael, P. , POHL, Gerald , REICHL, Richard , SPECK, Georg , KONETZKI, Ingo
IPC分类号： C07D451/10 , A61K31/46 , A61P11/06
CPC分类号： A61K45/06 , A61K31/46 , A61K31/537 , A61K2300/00
摘要： The invention relates to novel medicament compositions based on long-acting beta2 agonists and salts of a novel anticholinesterase drug (I), to methods for the production of these compositions and their use in treating respiratory tract diseases.
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公开(公告)号：EP1496902A1
公开(公告)日：2005-01-19
申请号：EP03712137.3
申请日：2003-04-09
发明人： BANHOLZER, Rolf , MEADE, Christopher, John, Montague , MEISSNER, Helmut , MORSCHHÄUSER, Gerd , PAIRET, Michel , PIEPER, Michael, P. , POHL, Gerald , REICHL, Richard , SPECK, Georg
CPC分类号： A61K31/56 , A61K31/46 , A61K31/4745 , A61K31/573 , A61K31/70 , A61K2300/00
摘要： The invention relates to novel medicament compositions based on long-acting steroids and salts of a novel anticholinesterase drug, to methods for the production of these compositions and their use in treating respiratory tract diseases.
摘要翻译： 本发明涉及基于长效类固醇和新型抗胆碱酯酶药物的盐的新型药物组合物，涉及这些组合物的制备方法及其在治疗呼吸道疾病中的用途。
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公开(公告)号：EP1494648A1
公开(公告)日：2005-01-12
申请号：EP03717247.5
申请日：2003-03-28
发明人： BANHOLZER, Rolf , GRAULICH, Manfred , KULINNA, Christian , MATHES, Andreas , MEISSNER, Helmut , SIEGER, Peter , SPECHT, Peter , TRUNK, Michael
CPC分类号： A61K9/0075 , A61K9/14 , A61K9/145 , A61K31/439
摘要： The invention relates to powdered preparations containing tiotropium for inhalation, processes for preparing them as well as their use for preparing a pharmaceutical composition for treating respiratory complaints, particularly for treating COPD (chronic obstructive pulmonary disease) and asthma.
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公开(公告)号：EP1496902B1
公开(公告)日：2005-12-14
申请号：EP03712137.3
申请日：2003-04-09
发明人： BANHOLZER, Rolf , MEADE, Christopher, John, Montague , MEISSNER, Helmut , MORSCHHÄUSER, Gerd , PAIRET, Michel , PIEPER, Michael, P. , POHL, Gerald , REICHL, Richard , SPECK, Georg
CPC分类号： A61K31/56 , A61K31/46 , A61K31/4745 , A61K31/573 , A61K31/70 , A61K2300/00
摘要： The invention relates to novel medicament compositions based on long-acting steroids and salts of a novel anticholinesterase drug, to methods for the production of these compositions and their use in treating respiratory tract diseases.
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公开(公告)号：EP1345936B1
公开(公告)日：2004-05-12
申请号：EP01990546.2
申请日：2001-12-12
发明人： BANHOLZER, Rolf , GRAULICH, Manfred , LUETTKE, Sven , MATHES, Andreas , MEISSNER, Helmut , SPECHT, Peter , BROEDER, Wolfgang
IPC分类号： C07D451/10
CPC分类号： C07D451/10
摘要： The invention relates to a novel method for producing (1α, 2β, 4β, 5α, 7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4-] nonane bromide.
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公开(公告)号：EP1345936A1
公开(公告)日：2003-09-24
申请号：EP01990546.2
申请日：2001-12-12
发明人： BANHOLZER, Rolf , GRAULICH, Manfred , LUETTKE, Sven , MATHES, Andreas , MEISSNER, Helmut , SPECHT, Peter , BROEDER, Wolfgang
IPC分类号： C07D451/10
CPC分类号： C07D451/10
摘要： The invention relates to a novel method for producing (1α, 2β, 4β, 5α, 7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4-] nonane bromide.
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公开(公告)号：EP1494648B1
公开(公告)日：2006-09-20
申请号：EP03717247.5
申请日：2003-03-28
发明人： BANHOLZER, Rolf , GRAULICH, Manfred , KULINNA, Christian , MATHES, Andreas , MEISSNER, Helmut , SIEGER, Peter , SPECHT, Peter , TRUNK, Michael
CPC分类号： A61K9/0075 , A61K9/14 , A61K9/145 , A61K31/439
摘要： The invention relates to powdered preparations containing tiotropium for inhalation, processes for preparing them as well as their use for preparing a pharmaceutical composition for treating respiratory complaints, particularly for treating COPD (chronic obstructive pulmonary disease) and asthma.
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公开(公告)号：EP1513838B1
公开(公告)日：2006-07-26
申请号：EP03720568.9
申请日：2003-05-16
IPC分类号： C07D451/06
CPC分类号： C07D451/06
摘要： The invention relates to a novel, technically applicable production method for preparing tropenol, optionally in the form of acid addition salts thereof.
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