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1.发明授权
公开(公告)号：EP1651224B1
公开(公告)日：2011-10-05
申请号：EP04741123.6
申请日：2004-07-17
IPC分类号： A61K31/4704 , A61K31/46 , A61K31/137 , A61K31/439 , A61P11/06
CPC分类号： A61K45/06 , A61K31/4704 , A61K2300/00
摘要： The present invention relates to novel pharmaceutical compositions comprising one or more, preferably one anticholinergic 1 and a betamimetic of formula 2 processes for preparing them and their use in the treatment of respiratory complaints.
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2.发明公开
公开(公告)号：EP1711480A1
公开(公告)日：2006-10-18
申请号：EP05700863.3
申请日：2005-01-13
发明人： HOENKE, Christoph , RUDOLF, Klaus , BOUYSSOU, Thierry , KONETZKI, Ingo , LUSTENBERGER, Philipp , MACK, Jürgen , SCHNAPP, Andreas , WIEDENMAYER, Dieter
IPC分类号： C07D265/36 , C07D413/12 , A61K31/538 , A61P11/08
CPC分类号： C07D265/36 , C07D413/12
摘要： The invention relates to compounds of formula (1), wherein groups X, Ra, Rb, R1, R1', R2, R2', R2'', R2''', V and n can have the meanings as cited in the claims and in the description, and to the use of these compounds as medicaments, particularly for treating inflammatory and obstructive respiratory diseases.
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公开(公告)号：EP1497289B1
公开(公告)日：2005-08-24
申请号：EP03746158.9
申请日：2003-04-09
发明人： BANHOLZER, Rolf , MEADE, Christopher, John, Montague , MEISSNER, Helmut , MORSCHHÄUSER, Gerd , PAIRET, Michel , PIEPER, Michael, P. , POHL, Gerald , REICHL, Richard , SPECK, Georg , KONETZKI, Ingo
IPC分类号： C07D451/10 , A61K31/46 , A61P11/06
CPC分类号： A61K45/06 , A61K31/46 , A61K31/537 , A61K2300/00
摘要： The invention relates to novel medicament compositions based on long-acting beta2 agonists and salts of a novel anticholinesterase drug (I), to methods for the production of these compositions and their use in treating respiratory tract diseases.
摘要翻译： 本发明涉及基于长效β2激动剂和新型抗胆碱酯酶药物（I）的盐的新型药物组合物，涉及这些组合物的制备方法及其在治疗呼吸道疾病中的用途。
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4.发明授权
公开(公告)号：EP1562603B1
公开(公告)日：2009-05-06
申请号：EP03778312.3
申请日：2003-11-11
发明人： BOUYSSOU, Thierry , BUETTNER, Frank , KONETZKI, Ingo , PESTEL, Sabine , SCHNAPP, Andreas , SCHOLLENBERGER, Hermann , SCHROMM, Kurt , HEINE, Claudia , RUDOLF, Klaus , LUSTENBERGER, Philipp , HOENKE, Christoph
IPC分类号： A61K31/538 , A61P11/00 , A61K31/535
CPC分类号： A61K31/538 , C07D265/36
摘要： The invention relates to the use of compounds of general formula (I), where the groups R1, R2 and R3 can have the meanings as given in the claims and description, for the production of a medicament for the treatment of COPD (Chronic Obstructive Pulmonary Disease) and novel compounds of general formula (I) as such.
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公开(公告)号：EP1654001A2
公开(公告)日：2006-05-10
申请号：EP04741127.7
申请日：2004-07-17
IPC分类号： A61K45/06 , A61P11/00 , A61P11/06 , A61K31/4704 , A61K9/12
CPC分类号： A61K9/008 , A61K9/0075 , A61K31/47 , A61K31/4704 , A61K31/56 , A61K2300/00
摘要： The present invention relates to novel pharmaceutical compositions comprising one or more, preferably one steroid 1 and a betamimetic of Formula (2) processes for preparing them and their use in the treatment of respiratory complaints.
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6.发明公开NEUE DIHYDROXY-METHYL-PHENYL-DERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DEREN VERWENDUNG ALS ARZNEIMITTEL 审中-公开新的二羟基甲基苯基衍生物，进程中为其及其作为药物
公开(公告)号：EP1562892A1
公开(公告)日：2005-08-17
申请号：EP03773711.1
申请日：2003-11-11
发明人： BOUYSSOU, Thierry , BUETTNER, Frank , KONETZKI, Ingo , PESTEL, Sabine , SCHNAPP, Andreas , SCHOLLENBERGER, Hermann , SCHROMM, Kurt , HEINE, Claudia
IPC分类号： C07C215/60
CPC分类号： C07C215/60
摘要： The invention relates to compounds of general formula (I), where the groups R1, R2, R3 and R4 can have the meanings given in the claims and description, method for production and use thereof as medicament, in particular for the treatment of inflammatory and obstructive airway diseases.
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7.发明授权
公开(公告)号：EP1711480B1
公开(公告)日：2007-12-19
申请号：EP05700863.3
申请日：2005-01-13
发明人： HOENKE, Christoph , RUDOLF, Klaus , BOUYSSOU, Thierry , KONETZKI, Ingo , LUSTENBERGER, Philipp , MACK, Jürgen , SCHNAPP, Andreas , WIEDENMAYER, Dieter
IPC分类号： C07D265/36 , C07D413/12 , A61K31/538 , A61P11/08
CPC分类号： C07D265/36 , C07D413/12
摘要： The invention relates to compounds of formula (1), wherein groups X, Ra, Rb, R1, R1', R2, R2', R2'', R2''', V and n can have the meanings as cited in the claims and in the description, and to the use of these compounds as medicaments, particularly for treating inflammatory and obstructive respiratory diseases.
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8.发明公开NEUE BETAMIMETIKA MIT VERLÄNGERTER WIRKUNGSDAUER, VERFAHREN ZU DEREN HERSTELLUNG UND DEREN VERWENDUNG ALS ARZNEIMITTEL 审中-公开NEWβ受体兴奋剂持续时间延长的效果，方法及其及其作为药物
公开(公告)号：EP1551792A1
公开(公告)日：2005-07-13
申请号：EP03750623.5
申请日：2003-09-25
发明人： BOUYSSOU, Thierry , BUETTNER, Frank , KONETZKI, Ingo , PESTEL, Sabine , SCHNAPP, Andreas , SCHOLLENBERGER, Hermann , SCHROMM, Kurt , HEINE, Claudia
IPC分类号： C07C217/70 , A61K31/135 , A61P11/06 , A61P17/00 , A61P9/06
CPC分类号： C07C217/70 , A61K31/137 , A61K31/18 , C07C2601/08 , A61K2300/00
摘要： The invention relates to compounds of general formula (I), where the groups R1, R2 and R3 can have the meanings given in the claims and the description, method for production and use thereof as medicaments, in particular for the treatment of inflammatory and obstructive bronchial diseases.
摘要翻译： 4-（2-（叔烷基氨基）-1-羟基乙基）-3 - 烷氧基 - 苯-1,2-二醇的衍生物（I）是新的。 （I），其中包括单独的光学异构体，对映体混合物和种族匹配，式Phenylethanolamines衍生物和它们的酸加成盐是新的。 R1，R2 = 1-4C烷基; R3 = 1-4C烷基或单或多取代的苯基; 或R2 + R3 =（CH 2）2或（CH 2）3
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9.发明公开
公开(公告)号：EP1720546A1
公开(公告)日：2006-11-15
申请号：EP05707250.6
申请日：2005-02-08
IPC分类号： A61K31/4196 , A61P11/06 , C07D249/08 , C07D405/04
CPC分类号： C07D249/08 , C07D405/04
摘要： The invention relates to the use of compounds of formula (I), in which the groups R1, R2, R3, R4 and n can be defined as cited in the claims and the description, for producing a medicament for the treatment of inflammatory and obstructive respiratory tract diseases. The invention also relates to novel compounds of formula (I) per se.
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10.发明公开3-HYDROXYMETHYL-4-HYDROXY-PHENYL-DERIVATE ZUR BEHANDLUNG VON ATEMWEGSERKRANKUNGEN 审中-公开3-羟甲基-4-羟基 - 苯基衍生物对呼吸系统疾病的治疗
公开(公告)号：EP1706389A1
公开(公告)日：2006-10-04
申请号：EP05700676.9
申请日：2005-01-04
发明人： BOUYSSOU, Thierry , BUETTNER, Frank , KONETZKI, Ingo , PESTEL, Sabine , SCHNAPP, Andreas , SCHOLLENBERGER, Hermann , SCHROMM, Kurt , HEINE, Claudia
IPC分类号： C07D249/08 , A61K31/4164 , A61P11/00 , A61K31/4196 , C07D233/54
CPC分类号： C07D249/08 , C07D233/64
摘要： The invention relates to the use of compounds of general formula 1 wherein the groups R1, X and Y have the designations cited in the claims and in the description, for producing a medicament for treating COPD (chronic obstructive pulmonary disease). The invention also relates to novel compounds of general formula 1, and to methods for the production thereof.
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