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公开(公告)号:EP1265596A2
公开(公告)日:2002-12-18
申请号:EP01920707.5
申请日:2001-03-23
发明人: LYONS, Robert, T. , DILLARD, David, H. , FIEGGEN, Bruce , RAUKER, Robert, M. , BLUNI, Scott, T.
IPC分类号: A61K9/107
CPC分类号: A61K9/0019 , A61B17/320758 , A61K9/1075 , B82Y5/00 , Y10S514/937 , Y10S514/938
摘要: A medical lubricant suitable for injection into the blood stream of a patient. The lubricant is suitable for use with rotating equipment such as atherectomy drive shafts moving within sheaths and over guide wires and other minimally invasive medical devices introduced into a patient through a catheter like instrument. The lubricant is an oil-in-water emulsion including a surfactant, a co-surfactant, and a pH buffer. The lubricant can further include a cryogenic agent and a pH adjusting agent. One lubricant includes olive oil as an emulsified oil, egg yolk phospholipid as a surfactant, sodium deoxycholate as a co-surfactant, glycerin as a cryogenic agent, L-histidine as a pH buffer, and is pH adjusted using sodium hydroxide. The lubricant can also include a therapeutic agent. The lubricant can withstand freeze/thaw cycles as well as saline dilution, heating, and shear stress without significant creaming, separation, or unacceptable increases in oil droplet size. Compared to saline, the lubricant provides significantly increased lubrication efficiency for rapidly moving parts.
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公开(公告)号:EP1885233A1
公开(公告)日:2008-02-13
申请号:EP06721148.2
申请日:2006-03-06
IPC分类号: A61B1/31
CPC分类号: A61B1/00082 , A61B1/31
摘要: An apparatus includes a body configured to be at least partially inserted into a rectum of a patient. The body defines a first passageway and a second passageway between a proximal end portion and a distal end portion. The first passageway is configured to receive a medical tool and the second passageway is configured to communicate an insufflation medium. An insufflation port is coupled to the second passageway and is configured to communicate the insufflation medium to the second passageway. A retention portion is coupled to the body and is configured to have a dimension transverse to an axis defined by the body sufficient to retain at least a portion of the body in the rectum. The retention portion is configured to be located beyond an anus of the patient.
摘要翻译: 一种装置包括构造成至少部分地插入患者的直肠内的主体。 主体限定第一通道和在近端部分与远端部分之间的第二通道。 第一通道构造成接收医疗工具,并且第二通道构造成连通吹气介质。 吹气端口联接到第二通路并且构造成将吹气介质传送到第二通路。 保持部分联接到主体并且构造成具有横向于由主体限定的轴线的尺寸,该轴线足以将主体的至少一部分保持在直肠中。 保持部分被构造成位于患者的肛门之外。
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公开(公告)号:EP1265596B1
公开(公告)日:2007-09-26
申请号:EP01920707.5
申请日:2001-03-23
发明人: LYONS, Robert, T. , DILLARD, David, H. , FIEGGEN, Bruce , RAUKER, Robert, M. , BLUNI, Scott, T.
IPC分类号: A61K9/107
CPC分类号: A61K9/0019 , A61B17/320758 , A61K9/1075 , B82Y5/00 , Y10S514/937 , Y10S514/938
摘要: A medical lubricant suitable for injection into the blood stream of a patient. The lubricant is suitable for use with rotating equipment such as atherectomy drive shafts moving within sheaths and over guide wires and other minimally invasive medical devices introduced into a patient through a catheter like instrument. The lubricant is an oil-in-water emulsion including a surfactant, a co-surfactant, and a pH buffer. The lubricant can further include a cryogenic agent and a pH adjusting agent. One lubricant includes olive oil as an emulsified oil, egg yolk phospholipid as a surfactant, sodium deoxycholate as a co-surfactant, glycerin as a cryogenic agent, L-histidine as a pH buffer, and is pH adjusted using sodium hydroxide. The lubricant can also include a therapeutic agent. The lubricant can withstand freeze/thaw cycles as well as saline dilution, heating, and shear stress without significant creaming, separation, or unacceptable increases in oil droplet size. Compared to saline, the lubricant provides significantly increased lubrication efficiency for rapidly moving parts.
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公开(公告)号:EP1257314B1
公开(公告)日:2005-06-15
申请号:EP01901905.8
申请日:2001-01-09
CPC分类号: A61M25/10184 , A61B17/12136 , A61M25/1011 , A61M25/10186 , A61M25/104 , A61M2025/1052
摘要: An occlusion device for occluding a body conduit including an elongate tubular shaft having an inflatable balloon disposed near the elongate shaft distal end and a proximal seal having a sufficiently small profile to allow a second catheter to pass over the distal occlusion device while the inflatable balloon remains uninflated. One occlusion device includes an elongate fluid displacement rod within the occlusion device elongate shaft, providing both a fluid pressure source and a seal. The elongate rod can be rapidly advanced and retracted, providing rapid and controlled inflation and deflation of the distal balloon. Also provided are alignment devices for aligning inflation fluid sources with occlusion device tubular proximal ends which can inject fluid through the device into the distal balloon.
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