-
公开(公告)号：EP1265596A2
公开(公告)日：2002-12-18
申请号：EP01920707.5
申请日：2001-03-23
发明人： LYONS, Robert, T. , DILLARD, David, H. , FIEGGEN, Bruce , RAUKER, Robert, M. , BLUNI, Scott, T.
IPC分类号： A61K9/107
CPC分类号： A61K9/0019 , A61B17/320758 , A61K9/1075 , B82Y5/00 , Y10S514/937 , Y10S514/938
摘要： A medical lubricant suitable for injection into the blood stream of a patient. The lubricant is suitable for use with rotating equipment such as atherectomy drive shafts moving within sheaths and over guide wires and other minimally invasive medical devices introduced into a patient through a catheter like instrument. The lubricant is an oil-in-water emulsion including a surfactant, a co-surfactant, and a pH buffer. The lubricant can further include a cryogenic agent and a pH adjusting agent. One lubricant includes olive oil as an emulsified oil, egg yolk phospholipid as a surfactant, sodium deoxycholate as a co-surfactant, glycerin as a cryogenic agent, L-histidine as a pH buffer, and is pH adjusted using sodium hydroxide. The lubricant can also include a therapeutic agent. The lubricant can withstand freeze/thaw cycles as well as saline dilution, heating, and shear stress without significant creaming, separation, or unacceptable increases in oil droplet size. Compared to saline, the lubricant provides significantly increased lubrication efficiency for rapidly moving parts.
-
公开(公告)号：EP1265596B1
公开(公告)日：2007-09-26
申请号：EP01920707.5
申请日：2001-03-23
发明人： LYONS, Robert, T. , DILLARD, David, H. , FIEGGEN, Bruce , RAUKER, Robert, M. , BLUNI, Scott, T.
IPC分类号： A61K9/107
CPC分类号： A61K9/0019 , A61B17/320758 , A61K9/1075 , B82Y5/00 , Y10S514/937 , Y10S514/938
摘要： A medical lubricant suitable for injection into the blood stream of a patient. The lubricant is suitable for use with rotating equipment such as atherectomy drive shafts moving within sheaths and over guide wires and other minimally invasive medical devices introduced into a patient through a catheter like instrument. The lubricant is an oil-in-water emulsion including a surfactant, a co-surfactant, and a pH buffer. The lubricant can further include a cryogenic agent and a pH adjusting agent. One lubricant includes olive oil as an emulsified oil, egg yolk phospholipid as a surfactant, sodium deoxycholate as a co-surfactant, glycerin as a cryogenic agent, L-histidine as a pH buffer, and is pH adjusted using sodium hydroxide. The lubricant can also include a therapeutic agent. The lubricant can withstand freeze/thaw cycles as well as saline dilution, heating, and shear stress without significant creaming, separation, or unacceptable increases in oil droplet size. Compared to saline, the lubricant provides significantly increased lubrication efficiency for rapidly moving parts.
-
公开(公告)号：EP1024791B1
公开(公告)日：2003-11-05
申请号：EP98946997.8
申请日：1998-09-14
IPC分类号： A61K9/107
CPC分类号： A61K9/1075 , A61B17/320758 , Y10S514/937 , Y10S514/938
摘要： A medical lubricant suitable for injection into the blood stream of a patient. The lubricant is suitable for use with rotating equipment such as atherectomy drive shafts moving within sheaths and over guide wires. The lubricant is an oil-in-water emulsion including a surfactant and a co-surfactant. The lubricant can include a cryogenic agent and a pH buffer and be pH adjusted. One lubricant includes olive oil as an emulsified oil, egg yolk phospholipid as a surfactant, sodium deoxycholate as a co-surfactant, glycerin as a cryogenic agent, L-histidine as a pH buffer, and is pH adjusted using sodium hydroxide. The lubricant can withstand freeze/thaw cycles as well as saline dilution, heating, and shear stress without significant creaming, separation, or unacceptable 15 increases in oil droplet size. Compared to saline, the lubricant provides significantly increased lubrication efficiency for rapidly moving parts.
-
公开(公告)号：EP1450729A1
公开(公告)日：2004-09-01
申请号：EP02790033.1
申请日：2002-12-06
发明人： GANTT, Samuel , FIEGGEN, Bruce
IPC分类号： A61F2/06
CPC分类号： A61F2/06 , A61F2002/061 , A61F2002/065 , A61F2240/001
摘要： An implantable textile prosthesis which is anatomically curved to substantially match the natural curvature of the aortic arch in a human being or patient is provided. The first woven section is arched define an apical region and to conform generally to an aortic arch of a human patient. A plurality of elongate woven tubular extents extend vertically from a top wall portion at the apical region of the tubular main wall. These tubular extents are sutured to the first woven section to provide fluid communication between the tubular main wall and the tubular extents.
-
公开(公告)号：EP1024791A1
公开(公告)日：2000-08-09
申请号：EP98946997.8
申请日：1998-09-14
IPC分类号： A61K9/107
CPC分类号： A61K9/1075 , A61B17/320758 , Y10S514/937 , Y10S514/938
摘要： A medical lubricant suitable for injection into the blood stream of a patient. The lubricant is suitable for use with rotating equipment such as atherectomy drive shafts moving within sheaths and over guide wires. The lubricant is an oil-in-water emulsion including a surfactant and a co-surfactant. The lubricant can include a cryogenic agent and a pH buffer and be pH adjusted. One lubricant includes olive oil as an emulsified oil, egg yolk phospholipid as a surfactant, sodium deoxycholate as a co-surfactant, glycerin as a cryogenic agent, L-histidine as a pH buffer, and is pH adjusted using sodium hydroxide. The lubricant can withstand freeze/thaw cycles as well as saline dilution, heating, and shear stress without significant creaming, separation, or unacceptable 15 increases in oil droplet size. Compared to saline, the lubricant provides significantly increased lubrication efficiency for rapidly moving parts.
-
-
-
-
搜索结果
5 条记录 (耗时 0.011 秒)
