摘要:
A stent having one or more beneficial agents which enhance the healing effect of the stent. The agent is positioned within a reservoir. The reservoir dynamically releases the agent when the stent is expanded. The reservoir makes use of various changes in stent shape during expansion to assure proper release of the agent. Agent release can be modulated at various points along the stent and with various rates of release. The reservoirs can also be cooperatively combined with features that enhance stent flexibility, structural integrity, and which prevent recoil.
摘要:
A stent (10) with strut bands (20) and connectors (40), wherein the strut bands have long (30) and short (32, 34) struts with a junction positioned between the short struts. Each junction defines a reservoir (12), wherein the reservoirs of a strut band are substantially circumferentially aligned. The connectors each have arms (42, 46), wherein each arm includes an opposing U-shaped link (44). The opposing links have a shared portion (50) disposed between a peak on one strut band and a longitudinally adjacent trough of an adjacent strut band.
摘要:
A stent has a plurality of members made from a first material. At least one of the plurality of members defines at least one hole. Each hole extends from a first surface of a member. Each hole has a first opening and a depth. Each hole has a barrier dividing the hole into a first reservoir and a second reservoir. The first reservoir extends from a first side of the barrier to the first opening of the hole and the second reservoir extends from a second side of the barrier to the second opening of the hole. The barrier is made from a material different from the first material. The barrier is semi-permeable and non-biodegradable and has a thickness which is less than the depth of the hole.
摘要:
A stent can include a tubular body, a plurality of circumferential serpentine bands, a plurality of connectors extending between immediately adjacent serpentine bands, and a plurality of tabs. The plurality of tabs include peak tabs and trough tabs. Each peak tab and each trough tab have a first end and a second end wherein only the first end is engaged to a serpentine band, each peak tab extends substantially parallel to the longitudinal axis from a peak on a serpentine band toward a peak on an immediately distal serpentine band. Each trough tab extends substantially parallel to the longitudinal axis from a trough on a serpentine band toward a trough on an immediately proximal serpentine band. Each serpentine band defines a plurality of holes and each tab defines a plurality of holes. The holes are constructed and arranged to contain a therapeutic agent.
摘要:
A bifurcation having a main branch portion and a side branch portion which interface about a frame. The frame is expandable from a first configuration enclosing a first area to a second configuration enclosing a second area wherein the second area is larger than the first area.
摘要:
Described herein are implantable medical devices, such as implantable or intravascular stents, for delivering a therapeutic agent, and methods for making such medical devices. In one embodiment, the medical device comprises a stent having a plurality of struts, at least one of which has a cavity disposed therein. A therapeutic agent is delivered from the cavity through an opening in a strut surface. In another embodiment, the medical device is a stent having a coating disposed on the side surface (s) of at least one strut for deliver of a therapeutic agent from the coating.
摘要:
A stent (10) may comprise a plurality of serpentine bands (20) , wherein adjacent serpentine bands (20) are connected by at least one connector strut (16) . A serpentine band (20) may comprise alternating straight struts (30) and s-shaped struts (32). Connector struts may comprise first connector struts (36) and second connector struts (38) , wherein the first connector struts (36) are nonparallel to the second connector struts (38) .
摘要:
Described herein are implantable medical devices, such as implantable or intravascular stents, for delivering a therapeutic agent, and methods for making such medical devices. In one embodiment, the medical device comprises a stent having a plurality of struts, at least one of which has a cavity disposed therein. A therapeutic agent is delivered from the cavity through an opening in a strut surface. In another embodiment, the medical device is a stent having a coating disposed on the side surface (s) of at least one strut for deliver of a therapeutic agent from the coating.